Striatal neurodegeneration in the presymptomatic phase of X-linked Dystonia-Parkinsonism
Objective: To identify structural brain changes in patients with X-linked dystonia-parkinsonism (XDP) and non-manifesting carriers of the TAF1 SVA retrotransposon insertion (NMC). Background: XDP is…Free Water in Corpus Callosum is Sensitive to Parkinson’s Disease-related Cognitive Decline
Objective: The objective of this study was to determine if the novel diffusion metric, free water (FW), from two-tensor modeling could sensitively identify microstructural alterations…Thalamic nuclei volumes and intrinsic thalamic network in motor subtype in Parkinson’s disease
Objective: The aim of this study is to investigate the alterations of thalamic nuclei volumes and intrinsic thalamic network in patients with de-novo PD according…In vivo markers of anxiety in drug-naïve Parkinson’s disease
Objective: To investigate imaging and CSF markers of disease pathology associated with anxiety in drug-naïve idiopathic Parkinson’s disease (PD) patients. Background: Anxiety is a frequent…Diagnostic accuracy of MR planimetry in clinically unclassifiable parkinsonism
Objective: To determine diagnostic accuracy of P/M, MRPI, and new indices termed P/M2.0 and MRPI2.0 (multiplying P/M and MRPI by third ventricle width/frontal horns width…Quantitative susceptibility mapping images for the parcellation of the Subthalamic Nucleus: a possible role for targeting Deep Brain Stimulation
Objective: To investigate the iron distribution in STN in PD patients using QSM images. Background: Subthalamic Deep Brain Stimulation (DBS) is considered an effective treatment…Leveraging patient-specific models to optimize DBS monopolar review
Objective: The objective of this study was to determine if patient-specific anatomical imaging can be leveraged to optimize monopolar review. Background: Parkinson’s disease (PD) is…Microstructural changes in GBA mutation carriers with depression
Objective: To investigate structural changes associated with depression in glucocerebrosidase (GBA) mutation carriers. Background: Depression is a common non-motor symptom in Parkinson’s disease (PD); however,…Progression of cortical thinning and neuropsychological decline in isolated Rapid Eye Movement sleep behavior disorder
Objective: We aimed to investigate the progression over time of cortical thickness and cognitive functions in isolated REM-sleep behaviour disorder (IRBD) compared to healthy controls (HC).…Automatic Detection of Nigrosome Degeneration in Susceptibility-Weighted MRI for Computer-Aided Diagnosis of Parkinson’s Disease Using Machine Learning
Objective: Automatize the detection of ‘swallow-tail’ appearance in substantia nigra dopaminergic neurons using MRI for more robust tests on Parkinson’s disease (PD) diagnosis. Background: Differential…
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