MR Conditional Labeling for DBS – Basic Physics for the Non-Specialist
Objective: A non-technical overview of the physics behind MR Conditional labeling for DBS devices and the implications for diagnostic imaging. Background: MRI is the recommended…Pattern of cerebral perfusion in early de novo Parkinson’s disease with mild cognitive impairment using voxel-based analysis of 3D arterial spin-labeling imaging
Objective: We aimed to investigate the patterns of cerebral perfusion in early de novo Parkinson’s disease (PD) patients with different cognitive states and to determine…Impulse control disorders in Parkinson’s disease: A whole brain morphometric and diffusion tensor study
Objective: To study morphometric and structural connectivity changes in the mesocorticolimbic pathway associated with the occurrence of impulse control disorders in Parkinson's disease. Background: Impulse…Decline in the midbrain-to-pons ratio over one year can support the differentiation between PSP and IPD
Objective: The midbrain-to-pons ratio (MTPR) is considered as an important diagnostic biomarker to differentiate between progressive supranuclear palsy (PSP) and idiopathic Parkinson’s disease (IPD). Here,…Open-label safety and tolerability of L-Dihydroxyphenylserine (L-DOPS) and high dose carbidopa therapy in Parkinson’s disease patients
Objective: To assess safety, tolerability, and central effects of L-Dihydroxyphenylserine (L-DOPS), in Parkinson’s disease (PD) patients treated with DOPA decarboxylase inhibition. Background: Norepinephrine (NE) is…Speculation on the timing of iron deposition in the putamen of patients with multiple system atrophy: multimodal MRI study
Objective: We sought to investigate the temporal pattern of iron deposition in the putamen of patients with multiple system atrophy (MSA) by calculating conditional probabilities…Different patterns of cortical and subcortical perfusion changes in essential tremor and tremor-dominant Parkinson’s disease using voxel-based analysis of 3D arterial spin-labeling imaging
Objective: We aimed to evaluate cerebral blood flow (CBF) in patients with untreated ET, de novo tremor-dominant PD (PDT) and age- and gender- matched controls…Structural changes in non-manifesting GBA mutation carriers and GBA mutation carriers with Parkinson’s disease
Objective: We aimed to investigate whether GBA mutations are associated with structural abnormalities in a cohort of GBA mutation carriers with and without manifested PD.…Impaired cerebral vasoreactivity in patients with Parkinson’s disease: clinical and imaging correlates
Objective: To determine the clinical and imaging correlates of impaired cerebral autoregulation as measured with cerebral vasoreactivity (CVR) in patients with idiopathic Parkinson’s disease (PD).…Investigation of 531 cases of neuromelanin sensitive imaging, about its characteristics by disease
Objective: To investigate the utility of Neuro-Melanin sensitive MRI (NMI) by 3T MRI for diagnosis, the relationship and severity in Parkinson's disease (PD) and related…
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