Copper chelation efficacy of alginate/chitosan based D-penicillamine nanoparticles in rat model of non-Wilsonian brain copper toxicosis
Objective: To evaluate the copper (Cu) chelation efficacy of orally administered D-penicillamine loaded nanoparticles to that of conventional D-penicillamine therapy for 90 days in Wistar…Creative thinking and parkinsonism: Preliminary clinical data on the role of frontal area
Objective: To evaluate divergent thinking (DT) by means of Abbreviated Torrance Test for Adults (ATTA) in Parkinsonism (PKS) with different deficit in cognitive functions. Background:…Preliminary results for a study on quality of life in Huntington’s disease patients and their caregivers in Peru
Objective: To quantitatively and qualitatively explore the determinants of quality of life (QOL) in Huntington's Disease (HD) patients and their caregivers in Peru. Background: HD…Study on association between physical and genetics role in essential tremor – A case control study
Objective: To elucidate the relationships between physical and genetics parameters in essential tremor patients and controls. Tremor is an involuntary, rhythmic shaking of any part…Differential expression of cerebral dopamine neurotrophic factor (CDNF) in the hippocampus and in the striatum of LRRK-2 mutant rat model of Parkinson’s disease
Objective: The objective of our study was to characterize the behavioral phenotype of the transgenic LRRK-2 rat in the context of PD model and to…Psychosis in Huntington’s disease
Objective: To describe the characteristics and phenomenology of psychotic symptoms in a Spanish cohort of HD patients. Background: Neuropsychiatric features are characteristic symptoms in Huntington's…EARLYSTIM: STN-DBS alleviates behavioural side effects of dopamine replacement therapy when compared to best medical treatment
Objective: To compare effects of STN-DBS and dopamine replacement therapy (DRT) on behaviour in PD in a 2 year follow-up study. Background: A large panel…Relationship of MDS-UPDRS non-motor symptoms to cognitive functioning in patients with Parkinson’s disease
Objective: To evaluate the relationship among individual items from the MDS-UPDRS Part I and measures of cognitive functioning in patients with PD. Background: Non-motor symptoms…
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