Closed loop spinal cord stimulation restores locomotion and desynchronizes corticostriatal beta oscillations
Objective: To test if closed loop Spinal Cord Stimulation (SCS) could be used to restore locomotion in a 6-hydroxydopamine (6-OHDA ) rodent model of Parkinson's…Directional Lead Impedances and Their Possible Effects on Deep Brain Stimulation
Objective: The objective was to characterize the possible effects that directional leads impedances have on Deep Brain Stimulation (DBS) therapy. Background: DBS of the subthalamic…Gender Differences in Parkinson’s disease: Transcranial Magnetics Stimulation Study of Newly Diagnosed Drug-Naïve PD Patients
Objective: In early Parkinson’s disease (PD), functional changes may be detected in primary motor cortex (M1) using transcranial magnetic stimulation (TMS). We hypothesised that, if…Pharmaeconomic study of the treatment of advanced Parkinson’s disease.
Objective: Conduct a comparative pharmacoeconomic analysis of the use of subcutaneous apomorphine infusion pump (SAIP), continuous levodopa/carbidopa duodenal infusión (LDI) and deep brain stimulation (DBS). Background:…Safe Functional MR Imaging in STN-DBS implanted Parkinson’s disease
Objective: Evaluation of clinically optimized settings in bilateral STN-DBS Parkinson’s disease, allows anatomical correlations with benefits and side effects. Background: MRI acquisition can cause permanent…Efficacy and tolerability of low-frequency deep brain stimulation during daytime only in Parkinson’s disease: a pilot study
Objective: To compare the efficacy and tolerability of low-frequency stimulation (LFS) during daytime only to LFS applied 24 hours a day, in PD patients bilaterally…Somnolence as untoward stimulation effect in subthalamic deep brain stimulation (STN DBS) for Parkinson’s disease (PD)
Objective: Excessive daytime sleepiness is a relatively common feature in PD. However, it has not been reported as a side effect of STN DBS. We…Deep Brain Stimulation (DBS) battery longevity of Medtronic Activa SC is briefer than preceding Soletra models, a within subject analysis
Objective: To contrast the durations of Activa SCs with the durations of preceding Soletra neurostimulator models within the same individuals programmed at near constant parameters.…Assessment of new technology in deep brain stimulation technology: what are the anticipated benefits?
Objective: To assess the ability of directional DBS leads and stimulation field shaping to provide more precisely targeted therapy. Background: Deep brain stimulation (DBS) has…The therapeutic effects of cortical electrical stimulation in an animal model of Parkinson’s disease
Objective: In this study, we first designed the long-term implantable cortical electrical stimulation (CES) module in a rat model of Parkinson's disease (PD). With the…
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