Rapidly progressive cognitive decline and hemi-dystonia due to anti-neuronal surface antibodies
Objective: To describe a case of marked asymmetric coarse tremor and dystonia in patient diagnosed with anti-NMDAR encephalitis. Background: Anti-NMDAR encephalitis has complex and heterogeneous…Brain neurotransmitters and neuropeptides alternations in Parkinson’s induced mouse models
Objective: Present study aimed to investigate the changes in brain neurotransmitters and neuropetides in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse models of PD. Background: Parkinson’s disease (PD), a…Neurorestorative effects of glycine transporter 1-inhibitor and D-Serine in a mouse model of nigrostriatal dopaminergic degeneration
Objective: We set out to evaluate potential neurorestorative effects of the GlyT1 inhibitor ACPPB vis-à-vis D-Serine in the intrastriatal 6-OHDA mouse model of Parkinson’s disease.…An extraordinary cause of psychosis: Anti-NMDA receptor encephalitis
Objective: Anti-N-methyl-D-aspartate (anti-NMDA) receptor encephalitis is an autoimmune encephalitis affecting predominantly young females. Background: It is characterized with neuropsychiatric symptoms, including personality changes, psychosis, autonomic…Effects of N-methyl-D-aspartate receptor antagonist in Parkinson’s disease with dementia
Objective: We conducted this longitudinal study to confirm the efficacy of memantine for PDD by analyzing comparative changes in regional cerebral blood flow (rCBF) and…Abnormal NMDA-related Electrophysiology in Parkinson Disease Dementia
Objective: Investigate mismatch negativity in Parkinson disease with dementia. Background: Parkinson’s disease with dementia (PDD) is an important cause of cognitive impairment in Parkinson’s disease…Modulation of CaMKIIa-NR2B interaction in levodopa-induced dyskinesia in 6-OHDA- lesioned Parkinson’s rats
Objective: In the present study, therefore, we examined the relationship between CaMKII and NR2B in levodopa-induced dyskinesia rats. Background: Long-term treatment with L-dopa leads to…Patient case reports supporting a long-term effect of sub-anesthetic ketamine infusion in reducing L-DOPA-induced dyskinesias
Objective: To evaluate possible long-term anti-dyskinetic activity of low-dose sub-anesthetic ketamine infusion from a retrospective chart review. Background: Repurposing drugs that have already been proven…Preclinical evaluation of sub-anesthetic ketamine infusion to reduce L-DOPA-induced dyskinesias: Is it a ‘chemical’ DBS?
Objective: To evaluate mechanism of long-term activity of sub-anesthetic ketamine infusion to reduce L-DOPA-induced dyskinesias (LID). Background: Ketamine is an anesthetic that, when administered as…The spectrum of abnormal movements and predictors of outcome in anti-NMDA receptor encephalitis in Thai patients
Objective: To describe the spectrum of abnormal movements and predictor of outcome in Thai patients with anti-NMDA receptor (NMDAR) encephalitis. Background: Anti-NMDAR encephalitis mostly presented…