A Phase 2 Randomized Controlled Trial Repurposing Ambroxol as a Disease Modifying Treatment for Parkinson’s Disease Dementia.
Objective: Currently there are no disease-treatments for Synucleinopathies including Parkinson’s disease dementia (PDD). Our objective is to use Ambroxol to target GBA/Glucocerebrosidase to treat PDD.…Early-onset Dementia with Lewy Bodies and Parkinson’s Disease Dementia: A Population-based Study (2010-2015).
Objective: To examine the incidence, clinical features, and survival of early-onset Dementia with Lewy Bodies and Parkinson’s Disease Dementia (DLB/PDD) (≤55 years of age) in…Exploring the Potential Anti-dementia Roles of Selected Herbal Anti-inflammatory Remedies in Parkinson’s Disease: Hopes and Challenges
Objective: To evaluate anti-dementia properties of the selected herbal anti-inflammatory remedies Background: Parkinson’s disease (PD) is the most common age-related neurodegenerative disease after Alzheimer’s disease.…Quantitative method for designing appropriate longitudinal follow-up frequency with application to Parkinson’s disease cognition research
Objective: To develop a quantitative method for designing appropriate longitudinal follow-up frequency. We demonstrate how to use this new method using a progression study of…Prevalence of Neuropsychiatric Symptoms in the Prodromal Stages of Dementia with Lewy Bodies and Parkinson’s Disease Dementia
Objective: Investigate neuropsychiatric features of prodromal stage dementia among individuals diagnosed with Lewy body disease. Background: There has been minimal investigation into the prodromal features…White Matter Changes and Early Cognitive Impairment in Parkinson’s Disease
Objective: Studying white matter changes in Parkinson's disease patients using diffusion tensor imaging; and its relation to cognition and motor symptoms impairment. Background: Cognitive dysfunction…Anxiety disorders are associated with verbal memory impairment in Parkinson’s disease
Objective: The present study aimed to investigate the association between anxiety disorders and memory impairment in Parkinson’s disease.The present study aimed to investigate the association…Clock Drawing Test does not Differentiate Alzheimer’s Disease from Parkinson’s Disease Dementia
Objective: Our focus was on comparing the performance of CDT and MMSE in Parkinson’s Disease Dementia (PDD) and Alzheimer’s Disease (AD) patients. Background: The mini…Clinical characteristics of pain in Parkinson’s disease dementia
Objective: The aim of this study was the assess the prevalence of pain in Parkinson’s disease dementia, its clinical characteristics, and correlations with motor part…When and how to stop subthalamic deep brain stimulation in late-stage Parkinson’s disease
Objective: We sought to investigate the percentage of “poor stimulation responders” among late-stage Parkinson's disease (LSPD) patients for elaborating an algorithm to decide whether and…
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