Safety of sublingual apomorphine film (APL-130277) for the treatment of OFF episodes in patients with Parkinson’s disease: Preliminary Results from a Phase III Study
Objective: To determine the safety of single treatments of APL-130277 in patients with Parkinson’s disease (PD). Background: Patients with Parkinson’s disease (PD) frequently develop problematic…Four year outcomes of a prospective, multi-center trial evaluating Deep Brain Stimulation with a new multiple-source, constant-current rechargeable system in Parkinson’s disease
Objective: To evaluate the four year, long-term follow up results of patients in the VANTAGE clinical study that employed multiple independent current control (MICC) Deep Brain…Five year longitudinal change in the MDS-UPDRS scores in early Parkinson’s disease participants: Results from the PPMI Study
Objective: To determine the longitudinal change in the Movement Disorder Society –Unified Parkinson’s Disease Rating Scale (MDS-UPDRS) in Parkinson’s disease (PD) participants who were untreated…A Phase 3 Study of isradipine as a disease modifying agent in patients with early Parkinson’s disease (STEADY-PD III): Baseline characteristics and study update
Objective: To evaluate the efficacy of isradipine 10 mg daily to slow progression of disability in early PD. Background: Isradipine, a dihydropyridine calcium channel antagonist,…Altered attentional brain network in Parkinson’s disease with mild cognitive impairment
Objective: To investigate alterations in the attention network in Parkinson’s disease patients with mild cognitive impairment (PD-MCI). Background: MCI is a risk factor for dementia…Early caudate involvement in Parkinson’s disease may predict future cognitive decline
Objective: 1. To investigate prevalence of caudate dopaminergic dysfunction as measured by 123I-FP-CIT in a large cohort of early stage (< 2 years disease duration)…The role of phosphodiesterase 4 in sleep disturbances in Parkinson’s disease
Objective: We aimed to assess the association between phosphodiesterase 4 (PDE4) expression and sleep disturbances in vivo using combined multimodal magnetic resonance imaging (MRI) and…First Report of Clinical Outcomes Resulting from Use of Directional Deep Brain Stimulation in Parkinson’s Disease and Essential Tremor
Objective: To evaluate clinical motor outcomes, the patient´s subjectively perceived benefit and the frequency of the use of directional lead stimulation in subjects with Essential tremor…Demographic and Clinical Characters of Parkinson’s Disease in Tertiary Hospital in Kuwait
Objective: To estimate the prevalence of Idiopathic Parkinson’s disease (PD) within patients attending a movement disorder clinic at tertiary hospital in Kuwait Background: PD is…Correlation and impact of non-motor symptoms on intensity of motor symptoms in Parkinson’s Disease
Objective: Tha aim of the study was to determine the relationship between the development of non-motor symptoms in the development of motor deficitis in patients…
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