Prognostic relevance and predictive ability of data-driven PD subtypes in the Longitudinal and Biomarker Studies in Parkinson’s disease (LABS-PD)
Objective: To assess the prognostic relevance and predictive ability of a PD subtype classification system generated in LABS-PD cohort. Background: PD subtype classification systems have…Plasma Biomarkers in Idiopathic Normal Pressure Hydrocephalus
Objective: (1) To investigate the role of plasma biomarkers that is known to related to Alzheimer’s disease in INPH(2) To assess the diagnostic and prognostic…Does Parkinsons KinetiGraph (PKG) recording help in clinical decision making? A local experience
Objective: To evaluate the use of the PKG to aid clinical management decisions in a district general hospital. Background: Clinicians treating Parkinson's disease (PD) must…More effective rTMS site for the freezing of gait in Parkinson’s disease
Objective: The aim of study is to find brain stimulation areas showing more effective response. Background: Freezing of gait (FOG) is frustrating problem in Parkinson’s…RBD predicts the cognitive impairment in Parkinson’s disease
Objective: To assess the relationship between the presence of Rapid eye movement sleep and behavior disorders RBD and the cognitive decline of non-demented patients with PD in…Validation of a performance-based assessment of functional ability related to cognition in Parkinson’s disease
Objective: Validate the University of California San Diego Performance-Based Skills Assessment (UPSA) in Parkinson's disease (PD) Background: Diagnostic criteria for PD dementia (PDD) require significant…Apolipoprotein E ε4 allele frequency in Korean Patients with Parkinson’s disease Dementia
Objective: The Apo E allele frequencies were evaluated in Korean patients with probable PDD diagnosed by the MDS task force criteria for the diagnosis of…A neuronal model of PARK20 (SYNJ1 mutation) using patient derived iPSCs
Objective: The SYNJ1 homozygous mutation (p.Arg258Gln) leads to juvenile Parkinsonism (PARK20). SYNJ1 plays an important role in synaptic vesicle cycling, and regulating autophagic flux. We…Genetic and pharmacological rescue of DJ-1 loss-of-function caused by a c.192G>C mutation in PARK7
Objective: In this study we investigate the cellular mechanism underlying the Parkinson’s disease (PD)-associated mutation c.192G>C in PARK7 and present a compound treatment that rescues…Absence of depression in de novo Parkinson’s disease: a benign motor phenotype?
Objective: This study aimed to assess the impact of early depression on motor deficits relative to the level of striatal dopaminergic depletion in patients with…
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