The impact of gastric acid suppressants and antacids on levodopa plasma concentration in patients with Parkinson’s disease
Objective: The levodopa tablet is prone to dissolve in acidic conditions. We investigated whether gastric acid suppressants (histamine-2 receptor antagonists or proton pump inhibitors) and…Deep brain stimulation in Parkinson’s disease: Outcome after more than nine years
Objective: The aim of this study is to examine the long-term effects of deep brain stimulation of the subthalamic nucleus (STN DBS) in Parkinson’s disease…Innovative recruitment strategies accelerate enrollment of genetic mutation carriers in the Parkinson’s Progression Markers Initiative (PPMI)
Objective: Determine feasibility of digital recruitment strategies, centralized screening, and a dedicated referral coordinator to enroll participants with LRRK2 or GBA mutations into PPMI, a…Efficacy and Safety of Therapeutic Interventions to Treat Motor Symptoms in Late Stage Parkinson’s Disease: A Systematic Review
Objective: Evaluate the efficacy and safety of therapeutic interventions to treat the motor symptoms in late stage PD. Background: PD patients in late stage are…Aberrant resting state functional brain networks in patients with Parkinson’s disease and visual hallucinations
Objective: To explore the neural correlates of Visual Hallucinations (VH) in patients with Parkinson’s disease (PD). Background: Psychosis is one of the commonly observed non-motor…Utility of DaTscan Imaging in Differentiating Drug Induced Parkinsonism from IPD and Other Forms of Parkinsonism
Objective: To determine clinical correlates which differentiate drug induced Parkinsonism (DIP) from IPD and other forms of Parkinsonism using DaT-SPECT imaging. Background: DaT-SPECT imaging is…Clinical characteristics of cognitive impairment in patients with Parkinson’s disease and its related pattern in 18F-FDG PET imaging
Objective: To characterize the clinical features and the neuroanatomical bases of cognitive impairment in Parkinson’s disease (PD) with respect to attention, executive function, memory, language,…Successful DBS: Doctors happy, patients not – Why?
Objective: Deep brain stimulation (DBS) in Parkinson's disease (PD) has been proven successful; however, not in all. Background: We report on 5 PD patients who…Evaluation of the accuracy of stereotactic DBS electrode implantation by post-operative image fusion
Objective: The precision in implantation of deep brain stimulation (DBS) electrodes based on pre-operative MRI planning is of utmost importance for the success of this…AntiParkinsonian medication adjustments following deep brain stimulation of subthalamic nucleus in patients with advanced Parkinson’s disease
Objective: We aimed to evaluate the long-term changes in medication of patients with advanced Parkinson's disease (PD) following STN-DBS in our center. Background: Usually antiParkinsonian…
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