The Faroese Parkinson’s diseases research program-Multifactorial analyses of a complex syndrome
Objective: The program aim is to assess the contribution of genes and environment influencing susceptibility, progression and the relative contribution of risk factors underlying Parkinson's…Analysis of the genetic variability in Parkinson’s disease from southern Spain
Objective: Our study was to assess the contribution of known genes in a cohort diagnosed with either familial (FPD) or early-onset sporadic PD (EOPD) from…Alpha-synuclein gene variants may predict neurostimulation outcome
Objective: We aim to predict both treatment efficacy and disease progression in PD patients with subthalamic nucleus deep brain stimulation therapy (STN-DBS) by genotyping of…Opioid K receptor variant delays the onset of dyskinesias in Parkinson’s disease
Objective: To investigate the genetic factors modulating the timing of the onset of levodopa-induced dyskinesias (LIDs) in Parkinson's disease (PD). Background: Pathophysiological mechanisms underlying LIDs…Long-duration response to levodopa in Parkinson’s disease is independent of disease duration: A prospective study on de novo patients in Ghana
Objective: To prospectively investigate the response to acute levodopa challenge in patients with advanced Parkinson's disease (PD) never treated before. Background: Pathophysiological mechanisms underlying motor…Discrimination of Parkinson’s disease participants from healthy controls using telephone-quality voice recordings
Objective: To test the practicality and efficacy of telephone-quality voice recordings to discriminate Parkinson's disease (PD) participants from healthy controls (HC). Background: Vocal performance degradation…Pharmacokinetic-pharmacodynamic effects of apomorphine sublingual film (APL-130277) for the rapid management of OFF episodes in patients with Parkinson’s disease
Objective: Determine the pharmacokinetic/pharmacodynamic effects of APL-130277 on OFF episodes in patients with Parkinson's disease (PD). Background: APL-130277 is a sublingual film being studied in…Increased cellular co-localization of tau fragment 1-368 and alpha-synuclein in two mouse model of Parkinson’s disease
Objective: To examine the distribution of a novel tau pathology and its interaction with alpha-synuclein in two mouse model of Parkinson's disease (PD). Background: Cleavage…MRI guided high-intensity focused ultrasond for the treatment of essential tremor and Parkinson’s disease: Clinical outcome and radiological findings of unilateral thalamotomy
Objective: To report our clinical experience in the treatment of essential (ET) and Parkinson's disease (PD) tremor with MRI guided High-Intensity Focused Ultrasound (MRgHIFU). Background:…Pronounced beta oscillations are a characteristic of the cortico-basal ganglia loop of subacute and chronic animal models of Parkinson´s disease
Objective: To compare the power spectral densities of local field potentials recorded from the cortico-basal ganglia loop of a subacute (reserpine) and a chronic (6-OHDA)…
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