Deep phenotyping of Parkinson‘s disease patients with the RAB32 Ser71Arg pathogenic variant and MDSGene literature review
Objective: To evaluate patients with PD and unaffected carriers of the pathogenic variant RAB32 p.Ser71Arg using a multimodal approach to gain insight into genotype-phenotype relationships…Examining the Gut Microbiome in Parkinson Patients with GBA Mutations
Objective: Gut dysbiosis is implicated in Parkinson disease (PD) pathogenesis, but less is known about the interaction of PD associated gene variants and gut microbiota.…Advancing Global Training and Capacity Building in Parkinson’s Genetics through GP2
Objective: To promote and facilitate learning by providing resources and expertise to address the training needs of the Global Parkinson’s Genetics Program (GP2; www.gp2.org) and…Rare Variants, Copy Number Variations, and Heritability Estimates in a Pilot Cohort of Egyptians with Parkinson’s Disease
Objective: To explore the genetic architecture of Parkinson's disease (PD) in Egypt, addressing the underrepresentation of this population in PD genetics research. Background: Genetic studies…Delirium following deep brain stimulation: An 8 year single-centre study
Objective: To describe the outcomes of patients undergoing deep brain stimulation (DBS) surgery for movement disorders and neuropsychiatric indications and characterise delirium symptoms. Background: Deep…Clinical Efficacy of a Novel Deep Brain Stimulation System with 16-contact Directional Leads for the Treatment of Parkinson’s Disease
Objective: To examine the effectiveness of a Deep Brain Stimulation (DBS) system with 16-contact Directional Leads for the treatment of Parkinson’s Disease (PD). Background: Directional…Sex-Based Differences in Perioperative Risks and Outcomes in Deep Brain Stimulation for Parkinson’s Disease: A Decade-Long ACS-NSQIP Analysis
Objective: To characterize sex-based differences in perioperative risk factors and early postoperative outcomes in Deep Brain Stimulation (DBS) for Parkinson’s disease (PD) using the American…Comparison of subthalamic nucleus and globus pallidus internus as deep brain stimulation targets for freezing of gait in Parkinson’s disease
Objective: To compare the short-term effects of deep brain stimulation (DBS) in subthalamic nucleus (STN) and globus pallidus internus (GPi) on freezing of gait (FOG)…Qigong Exercise on Nonmotor Symptoms in Parkinson’s Disease
Objective: This randomized controlled clinical trial examined the efficacy of a Qigong exercise on non-motor symptoms in people with Parkinson’s disease (PD). Background: Non-motor symptoms…Neural Correlates of Impaired Apathy Self-awareness in Parkinson’s Disease
Objective: To examine the presence of apathy self-awareness in PD patients using a dimensional approach Background: Apathy, or loss of motivation, is a common neuropsychiatric…
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