Evaluation of Motor Function Using Motor Testing App and Deep Learning for the Treatment of Lewy Body Dementia
Objective: To construct deep learning (DL) models using finger tapping data and apply them in PRESENCE to evaluate treatment effect in motor function. Background: PRESENCE…Re-thinking enrollment of Deep Brain Stimulation patients in Parkinson’s Disease Clinical Trials
Objective: To report on a survey of Parkinson’s disease (PD) experts on the inclusion of PD patients with deep brain stimulation (DBS) in clinical trials.…Parkinson Progression Marker Initiative – New Science/New Cohorts
Objective: The Parkinson Progression Marker Initiative (PPMI) is expanding its cohorts and exploring additional biomarkers of PD progression to test hypotheses of the underlying molecular…Impact of specialized light therapy in Parkinson’s disease on MDS-UPDRS parts 1-3 subscales
Objective: An exploratory analysis to examine the MDS-UPDRS 1-3 subitems of PD patients who underwent specialized light therapy (SLT) to assess the breadth of impact…Safety, tolerability and CNS effects after single and multiple doses of β-agonists in healthy volunteers and patients with Parkinson’s disease
Objective: This study aimed to assess the effects of β-agonists on central nervous system (CNS) functioning in healthy volunteers and patients with Parkinson’s disease. Background:…Effects of Once-Daily Opicapone 50 mg on the Pharmacokinetics of Levodopa Administered as Carbidopa/Levodopa Extended-Release Capsules: An Open-Label Phase 1 Study
Objective: To assess the effects of opicapone 50 mg on the pharmacokinetics (PK) of levodopa (LD) and its metabolite, 3-O-methyldopa (3-OMD), when administered with oral…Community-Based Multidisciplinary Program for People with Parkinson Disease: A 2-year comparison
Objective: The current study reports outcomes from a 2 year-long community-based multidisciplinary program for individuals with Parkinson disease (PD) and their families based in Oklahoma…Local Field Potentials (LFP) used to guide treatment of biphasic dyskinesias in a patient with Parkinson’s Disease (PD)
Objective: To identify, characterize and treat dyskinesias and off time in a patient with PD via the use of gamma and beta peak LFP using…Transcranial Magnetic Stimulation in Parkinsonism. Tremor and Biomechanics Evaluation
Objective: The aim of our study was to reveal the relationship between motor and muscle activity шт terms of plantar pressure distribution PPD) in Parkinson's…Challenges in Implementing Relevant Exercise Interventions in Mouse Models of Parkinson’s Disease
Objective: To determine the suitability of a motorized wheel as a forced exercise modality that does not rely on aversive stimuli for use in Parkinson’s…
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