Optimizing patient-centric clinical outcome assessments for use in Parkinson’s disease clinical trials: Critical Path for Parkinson’s multistakeholder initiative
Objective: To advance patient-centric endpoints for use in early-stage Parkinson’s disease (PD) clinical trials. Background: Limitations with currently available patient-centric clinical outcome assessments (COAs) has…Factors related to the antidepressant effect of safinamide in Parkinson’s disease. A post-hoc analysis of SADNESS-PD study
Objective: To assess the role of different factors in the antidepressant effect of safinamide in Parkinson’s disease (PD) Background: SADNESS-PD was a real-life, multicenter, retrospective…Alprazolam reduces freezing of gait and improves freezing-related gait measures
Objective: We investigated the effect of acutely reducing anxiety with the benzodiazepine, Alprazolam, on freezing of gait (FOG) in patients with Parkinson’s disease (PD). Background:…Relationship between gait speed and functional measurements in Parkinson’s disease
Objective: The present study aims to relate gait speed in Parkinson's disease (PD) with functional measures of muscle strength, balance and physical capacity. Background: PD…Rapid onset of good ON time and improvement in motor-state stability in aPD patients after treatment with continuous subcutaneous foslevodopa/foscarbidopa
Objective: To evaluate time to ON without troublesome dyskinesia (‘good ON’) and patterns of motor-state stability throughout the day in patients with advanced Parkinson’s disease…Deep Brain Stimulation in Parkinson’s disease: Challenges of a young experience in southern Morocco
Objective: The objective of our research was to describe the epidemiological, therapeutic features and effectiveness of deep brain stimulation in operated patients. To cite the…MoCA and MMSE subitems’ sensitivity across the PD-cognitive spectrum
Objective: To determine which Montreal Cognitive Assessment (MoCA) and Mini-Mental State Examination (MMSE) subitems are more sensitive in detecting cognitive abnormalities in patients with PD…Polypharmacy and drug-related problems in geriatric patients with Parkinson’s Disease
Objective: To identify and address polypharmacy and drug related problems (DRPs) in geriatric patients (>65 years old) in an Integrated Parkinson’s Disease clinic. Background: Management…Climb up! Head up! Climbing improves posture in Parkinson’s disease. A randomised controlled trial.
Objective: We investigated the role of sport climbing in correcting stooped posture in Parkinson Disease patients. Background: Parkinson’s Disease (PD) is a neurodegenerative movement disorder…Data-driven identification of distinct fronto-subcortical and cortical-posterior subtypes of cognitive decline in Parkinson’s disease
Objective: To use a novel data-driven approach, Subtype and Stage inference (SuStain)[1], for identifying distinct subtypes of domain-specific cognitive decline in Parkinson’s disease (PD), and…
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