Combining intraoperative microelectrode recordings with postoperative transcranial B-mode sonography of the brainstem to estimate the anatomical position of the electrode for chronic subthalamic nucleus deep brain stimulation in Parkinson´s disease
Objective: We tested whether the position of the electrode for deep brain stimulation (DBS) could be assessed relative to subthalamic nucleus (STN) dorsal boundaries by…Spinal cord stimulation for gait problems in Parkinson´s disease: Long term report and placebo viability
Objective: In the present study we set out to report a very long-term follow-up period of spinal cord stimulation (SCS) for Parkinson's Disease (PD) patients…Knowledge and attitude of Egyptian general public towards Parkinson disease: A cross-sectional study in Egypt.
Objective: We aim to investigate the public Egyptian knowledge and attitude towards PD. Background: In Egypt, the PD prevalence reached 316.50 per 100,000 people. Given…Psychometric characteristics of the Neuropsychiatric Fluctuation Scale
Objective: To evaluate the psychometric properties of the Neuropsychiatric fluctuation scale (NFS) for Parkinson’s disease (PD). Background: Neuropsychiatric fluctuations (NpsyF) in PD are frequent and…Quality of life and patient reported outcomes with subcutaneous levodopa/carbidopa infusion: Findings from the ND0612 BeyoND study
Objective: To review quality of life and other patient reported outcomes data from the ND0612 BeyoND study. Background: ND0612 is in development as a continuous,…Impact of istradefylline on the adjustment of levodopa dose escalation in Parkinson’s disease: Results of the ISTRA ADJUST PD randomized, controlled study
Objective: To evaluate the effect of istradefylline (IST), an adenosine A2A receptor antagonist, on the adjustment of levodopa dose escalation in patients with Parkinson’s disease…Computer vision can detect changes in bradykinesia associated with dopaminergic state in Parkinson’s disease
Objective: To evaluate the classification accuracy of a computer vision-based feature extraction and classifier method to detect changes in finger tap bradykinesia associated with dopaminergic…A case with clinical features of alpha-synuclein- and tauopathy: Genetic and histopathological workup.
Objective: Here, we present a clinical case that mimicked the coincidence of idiopathic Parkinson’s disease (PD) and tauopathy. Background: Mutation in leucine-rich-repeat-kinase 2 (LRRK2) gene…Multimodal mechanistic disease stratification in sporadic Parkinson’s disease
Objective: To mechanistically stratify Parkinson’s disease (PD), applying a combination of putaminal 31Phosphorus magnetic resonance spectroscopy (31P-MRS) with detailed assessment of mitochondrial and lysosomal function…Concomitant Medication Use and Levodopa Equivalent Daily Dose Requirements After Foslevodopa/foscarbidopa Initiation
Objective: To evaluate patterns of concomitant medication use and levodopa equivalent daily dose (LEDD) during a 52 week study with foslevodopa/foscarbidopa (LDP/CDP). Background: LDP/CDP is…
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