Association of a new pathogenic variant of LRRK2 with modifying lysosomal genes in a family with Parkinson’s disease
Objective: To characterize a Parkinson’s disease (PD) family with high recurrence of the disease. Background: Parkinson’s disease (PD) is a complex neurodegenerative disorder in which…Genome-wide association study of Aβ, t-tau and p-tau in CSF in Parkinson’s disease
Objective: To investigate genetic contributions to the Alzheimer’s disease (AD) related cerebrospinal fluid (CSF) biomarkers in the patients with Parkinson’s disease (PD). Background: Aβ, t-tau…Clinically interpretable severity estimation of facial expression impairment in Parkinson’s disease
Objective: To develop a scalable and interpretable computer-vision based algorithm to measure the severity of facial impairment in Parkinson’s disease. Background: Neurological disorders frequently manifest…Design of a prodromal screening study for subtypes in Parkinson’s Disease
Objective: To follow-up prodromal Parkinson’s Disease (PD) subtypes in a longitudinal cohort study, validating new biomarkers and ethical guidelines for early detection of PD. Background:…High preoperative gait variability is a prognostic predictor of gait and balance in Parkinson disease patients with deep brain stimulation
Objective: To elucidate the objective biomarker for long-term outcome of STN DBS in PD patients, we investigated the value of pre-operative quantitative gait parameters for…Plasma Alzheimer’s disease biomarkers and cognitive progression in Parkinson’s disease
Objective: To evaluate the relationship between plasma Alzheimer's disease biomarkers and cognitive progression in Parkinson's disease Background: Plasma phosphorylated tau (ptau) isoforms have been recently…Motor and non-motor features of Parkinson’s disease in a large cohort of Gaucher’s disease patients
Objective: To investigate the prevalence of PD motor and non-motor clinical features and to characterize the prodromal phase of PD in a cohort of GD…Automatic Speech Recognition for speech therapy in a Parkinson’s disease patient
Objective: The aim of the present study was to examine the Automatic Speech Recognition (ASR) technology as a useful approach to enhance the speech intelligibility…Incidental Lewy Body disease and idiopathic Parkinson’s disease: from common pathogenic factors to the overlapping clinical features
Objective: To compare established early symptoms and risk factors associated with Parkinson’s disease (PD) in a cohort of incidental Lewy Body disease (iLBD) and healthy…Impact of the delayed diagnosis in the prognosis of Parkinson’s disease.
Objective: To evaluate the difference of motor and non-motor dysfunction, and quality of life in Parkinson’s disease (PD) patients with and without delayed diagnosis. Background:…
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