Association Between Sleep Disturbance and Fatigue in Patients with Parkinson’s Disease
Objective: This study aimed to comprehensively investigate the associations between sleep disturbance and several non-motor symptoms, with a particular focus on the relationship with fatigue.…Effects of Personalized Visual and Auditory Cueing on Sit-to-Stand Biomechanics in Individuals with Parkinson’s disease: A Subgroup Analysis
Objective: To investigate the effects of personalized visual and auditory cueing combined with task-specific sit-to-stand training on movement kinematics, functional mobility, and psychosocial outcomes in…Risk of Ischemic Cerebrovascular Events in Patients with Deep Brain Stimulation for Parkinson’s Disease: A Cohort Study
Objective: To longitudinally assess the risk of ischemic cerebrovascular events in patients undergoing DBS Background: Longitudinal data on the potential impact of DBS on long-term…Extended long-term follow-up of adaptive deep brain stimulation in Parkinson’s disease
Objective: To evaluate the extended long-term durability, programming stability, and safety of adaptive deep brain stimulation (aDBS) in people with Parkinson’s disease (PD). Background: Adaptive DBS is a recently available enhancement to continuous DBS (cDBS) that dynamically adjusts stimulation amplitude based on neural…Semiquantitative [¹²³I]FP-CIT SPECT metrics combined with machine learning improve clinical differentiation of parkinson’s disease and atypical parkinsonian syndrome
Objective: To evaluate the capacity of semiquantitative striatal [¹²³I]FP-CIT SPECT-derived metrics to improve the clinical differentiation of degenerative parkinsonism through an integrated machine learning model.…Consistent Motor Benefit of Safinamide across Clinically Relevant Subgroups in Japanese Patients with Parkinson’s Disease: A 24-Week Real-World Study
Objective: To evaluate changes in motor symptoms after safinamide initiation in Japanese patients with Parkinson’s disease (PD) in real-world clinical practice. Background: Safinamide, a monoamine…Decoding Deep Brain Activity from Cortical Signals using Deep Learning across Movement Disorders
Objective: To develop and validate a deep learning framework for reconstructing subcortical neural activity from cortical electrocorticography (ECoG), enabling continuous deep brain biomarker inference without…Global Parkinson´s Symptoms Index Correlates with Changes in Quality of Life and Autonomy for Activities of Daily Living
Objective: The aim of the present study was to know if a global assessment of Parkinson's disease (PD) using a new proposed index correlated with…Neuronal aSynuclein Disease Integrated Staging System (NSD-ISS) Reveals Clinically Meaningful Functional Progression and Quality-of-Life Impact in Parkinson’s Disease
Objective: To evaluate the utility of the Neuronal aSynuclein Disease Integrated Staging System (NSD-ISS) in assessing the meaningfulness of stage progression, and associations with quality…A composite oculomotor biomarker for differentiating Parkinson’s disease from multiple system atrophy
Objective: To evaluate whether a composite oculomotor index integrating multiple eye movement domains improves discrimination between PD and MSA. Background: Differentiating Parkinson’s disease (PD) from…
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