Initial longitudinal analyses of objectively assessed cognitive functional abilities in a cohort with Parkinson’s disease
Objective: Detect the earliest changes in cognitively demanding activities of daily living in Parkinson's disease (PD) and determine their relationship with changes in global cognition…White matter and cognition in Parkinson’s disease
Objective: Examine whether a recently developed MRI biomarker intended to assess cerebrovascular small vessel disease, peak width of skeletonized mean diffusivity (PSMD)[1], predicts cognitive decline…Genotypic and phenotypic spectrum of PINK-1 associated parkinsonism in 44 mutation carriers from 11 Tunisian families
Objective: To characterize the family history and clinical features of mutations of the PINK-1 gene in a cohort of Tunisian patients with Parkinson disease (P.D)…East Asian Parkinson’s Disease Genomics Consortium – An introduction
Objective: To further understand the genetic architecture of Parkinson’s disease (PD) in East Asian and to establish a consortium that collaborates on genetic studies in…LIPAD (LRRK2/Luebeck) International Parkinson’s Disease Study: Protocol and feasibility study
Objective: To systematically assess clinical signs and symptoms including non-motor features, comorbidities, medication and environmental factors in 1,000 participants internationally: 300 with LRRK2 (Leucine-rich repeat…Next-generation sequencing of plasma-associated extracellular vesicle miRNAs as potential biomarkers for Parkinson’s disease and its prodromal stage
Objective: This study aimed to identify subsets of plasma EV-associated miRNAs with diagnostic potential for PD and iRBD, the prodromal stage of PD. Background: Parkinson’s…Cortical microstructural alterations are more sensitive than morphology changes to cortical degeneration in Parkinson’s disease with mild cognitive impairment
Objective: To compare the sensitivity of detection cortical degenerative changes in patients with Parkinson’s disease (PD) and mild cognitive impairment (MCI) between the diffusion magnetic…EVOLUTION OF PARKINSON’S DISEASE IN PATIENTS WITH ESSENTIAL TREMOR: CLINICAL AND NEUROIMAGING ASPECTS
Objective: Analyze the result of the SPECT-TRODAT image exam in patients with ET and to evaluate the predictive value of a possible evolution to the…Sexual divergencies in monoaminergic projections in Parkinson’s disease: a 123I-FP-CIT SPECT study
Objective: To investigate sex differences in nigrostriatal and extrastriatal 123I-FP-CIT SPECT monoaminergic projections in healthy subjects and Parkinson’s disease (PD) Background: preclinical and clinical studies suggest…Dysfunctional resting connectivity in early stage of Parkinson’s disease is indistinguishable from connectivity in REM sleep behaviour disorder
Objective: To investigate the differences in functional connectivity among healthy subjects (HC), patients with REM sleep behaviour disorder (RBD) and levodopa-naïve patients in early stage…
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