The study of genetic factors in motor levodopa-induced complications development in Russian patients with Parkinson’s disease
Objective: The aim of our study is to search for genetic risk factors for the development of motor side effects of dopaminergic therapy, such as…Building a Global Parkinson’s Genetics Program (GP2): Clinical Cohorts Integration Working Group
Objective: To recruit Parkinson's Disease (PD) cohorts across the world for the global Parkinson's Genetics Program (GP2, http://gp2.org/), harmonise clinical data across cohorts for joint…Stratified genome-wide association study revealed novel interactions for the top hit Parkinson’s disease loci.
Objective: To identify genetic modifiers and interactors that may modulate known risk variants in the SNCA, TMEM175 and MAPT loci in Parkinson’s disease (PD). Background:…Targeted plasmaproteome identifies a distinct biomarker panel in early and prodromal Parkinson’s disease
Objective: To identify protein biomarkers in plasma of patients with Parkinson’s disease (PD). Background: Inflammation plays a key role in the initiation and progression of…PD phenotype with premotor RBD is associated with a dysbiotic profile of gut microbiota.
Objective: The aim of the study was to compare the fecal microbial composition of a group of PD patients with and without premotor RBD. Background:…Cerebral white matter atrophy may be associated with the performance of activities of daily livings in patients with Parkinson’s disease
Objective: To assess whether global or regional brain structural abnormalities are associated performance of activities of daily livings (ADL) in patients with Parkinson's disease (PD).…Patterns of Cortical Thinning in Patients with Parkinson’s Disease
Objective: To investigate patterns of cortical thickness that are associated with disease severity and response to levodopa. Background: Cortex affection is a neuropathological correlate of…Relationship of subcortical iron deposition and mitochondrial dysfunction in patients with idiopathic Parkinson’s disease
Objective: To investigate subcortical brain iron deposition as a potential predictor of the bioenergetic status in patients with idiopathic Parkinson's disease. Background: The underlying pathophysiology…Analysis of brain structural connectivity networks and white matter integrity in patients with early Parkinson’s disease: a longitudinal study
Objective: The objective of this study was to analyze the differences in structural connectivity and white matter (WM) microstructural integrity in people with early-PD over…Impact of the postural function сhanges on quality of life and daily activity in patients with Parkinson’s disease during DBS
Objective: Quality of life (QOL) and activity of daily living (ADL) in PD patients depends on the severity of motor disorders, including changes of postural…
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