EPIDEMIOLOGICAL OVERVIEW OF PARKINSON’S DISEASE IN BRAZIL
Objective: To describe the epidemiological profile in patients hospitalized with Parkinson's Disease in Brazil during the years 2015 to 2020. Background: Parkinson's disease (PD) is…Machine Learning (ML) Prediction of Parkinson’s Disease (PD) Risk and Nigral Neuron Density
Objective: To investigate associations between nigral neuron density and ML-based PD risk prediction. Background: Early identification of persons at high risk for developing PD is…Plasma phosphorylated α-synuclein relates to cognitive impairment in patients with Parkinson’s disease
Objective: To investigate whether plasma phosphorylated α-synuclein (p-syn) were associated with cognitive function in Parkinson’s disease (PD). Background: Parkinson’s disease (PD) is the second most…Comparisons Between Parkinson’s Disease Patients and At-Risk Individuals: Can Olfactory Deficits and Cognitive Measures Serve as Preclinical Markers?
Objective: To examine whether individuals at increased risk of developing Parkinson’s disease (PD) show specific cognitive impairments suggestive of progression towards PD. Background: Olfactory deficits…Parkinson’s-disease risk variants are differentially associated with discrete phenotypic characteristics of Parkinson’s-disease at baseline.
Objective: Evaluate whether genetic risk variants for Parkinson’s disease discovered in case-control GWAS uniformly or differentially contribute to the clinical phenotype of PD. Background: Genetic…Monogenic Hub of the Global Parkinson’s Genetics Program (GP2): The 500-genomes pilot project
Objective: To identify novel monogenic causes of Parkinson’s disease (PD). Background: The Global Parkinson’s Genetics Program (GP2, http://gp2.org/) is an international collaborative effort that aims…Genetic factors associated with dementia in Parkinson’s disease in the Parkinson’s Incidence Cohorts Collaboration (PICC)
Objective: To evaluate the effect of genetic variants in β-glucocerebrosidase (GBA), apolipoprotein E (APOE), microtubule-associated protein tau (MAPT), and α-synuclein (SNCA) loci on the risk…Parkinson’s disease-linked LDL Receptor Related Protein 10 (LRP10) is implicated in regulation of the secretory and autophagy-lysosome pathways
Objective: We aim to investigate the potential roles of LRP10 defects in PD, PDD and DLB, focusing on two pathways known to be central in…Induction of Parkinsonian-like changes via targeted down-regulation of astrocytic glutamate transporter GLT-1 in the striatum
Objective: The aim was to explore the function and mechanism of astrocytic GLT-1 in PD-like changes. Background: Numerous researches suggest decreased expression of glutamate transporter-1…DO FREEZING OF GAIT AND GAIT AUTOMATICITY IN PARKINSON’S DISEASE SHARE THE SIMILAR NEURAL SUBSTRATE?
Objective: To verify if freezing of gait (FOG) in Parkinson’s disease (PD) and gait automaticity share a similar neural substrate. Background: FOG in PD may…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.