Identification of underlying Lewy body pathology in primary tauopathies by α-synuclein seed amplification assay
Objective: To determine intravitam prevalence of α-synuclein (αSyn) pathology in primary tauopathies, such as PSP and CBS, by αSyn seed amplification assay (synSAA) Background: Neuropathological…PSP: a Clinical Case
Objective: PSP is traditionally considered a neurodegenerative disease of late life. Its diagnostic criteria include the item “age of onset over 40 years.” This significantly…Hierarchical Machine Learning Classification of Parkinsonian Disorders using Saccades
Objective: To evaluate the discriminative power of a novel saccade waveform reconstruction approach compared to conventional saccadic metrics in differentiating Parkinson's disease (PD), progressive supranuclear…Dermal 4R-Tau seeding as a novel biomarker for Progressive Supranuclear Palsy
Objective: To ascertain the presence of misfolded tau species in the skin of Progressive Supranuclear Palsy (PSP) patients and evaluate its utility as a potential…The links between frontal deficits and levels of inflammatory parameters in Progressive Supranuclear Palsy
Objective: The goal of the research was to verify the possible association between the levels of inflammatory factors and frontal deficits in Progressive Supranuclear Palsy…Validation of Inertial Monitoring Units for Gait Assessment in Progressive Supranuclear Palsy
Objective: To evaluate the validity and precision of using inertial measurement units (IMU) for measurement of kinematics and spatial-temporal features of gait in progressive supranuclear…Linear Mixed-Effect Modelling of Antisaccades in Parkinson’s Disease and Progressive Supranuclear Palsy
Objective: This study aims to investigate variations in antisaccade parameters (latency, damping ratio, peak velocity, and amplitude) among different stages of Parkinson's Disease (PD), Progressive…Legmain/Asparaginyl endopeptidase-resistant tau fibril fold produces corticobasal degeneration-specific C-terminal tau fragment
Objective: This study monitored the formation of CBD (corticobasal degeneration)-type fibrils that exhibit astrocytic plaques, a characteristic CBD pathology, using Legumain-cleavage site-specific antibodies and CBD-specific…Peripheral inflammation severity in differential diagnosis of progressive supranuclear palsy and multiple system atrophy – usefulness of neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio and neutrophil-to-high-density lipoprotein-cholesterol ratio
Objective: Assessment of the possible differences in peripheral inflammation severity between progressive supranuclear palsy (PSP) and multiple system atrophy (MSA) with the use of three…Ethnic Diversity and Symptomatology in Parkinson’s Disease with a Focus on Falls and Vertical Gaze Palsy
Objective: The objective of this study was to explore atypical features in the clinical phenotype of people with Parkinson’s disease (PwP) enrolled in the East…
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