Can we stage tau pathology in PSP?
Objective: To evaluate distribution pattern of tau pathology in different PSP clinical subtypes and develop a staging system. Background: Progressive supranuclear palsy (PSP) is a…Identification and characterization of anti-prionic compounds that disassemble Tau prions as a novel therapeutic approach for tauopathies
Objective: Stabilization of monomeric Tau protein by transient and high-affinity binding ligands is a novel and highly innovative anti-prionic treatment strategy for tauopathies. Background: Tauopathies…Successful treatment of incessant purposeless groaning in Progressive Supranuclear Palsy with Pimozide
Objective: Evaluation of therapeutic options for a patient of Progressive Supranuclear Palsy (PSP) presenting with incessant purposeless groaning. Background: PSP is a neurodegenerative disorder characterized…Mass spectrometry-based proteomics brain analysis to distinguish between Parkinson syndromes
Objective: To address the gap existing during clinical diagnosis in differentiating among various forms of Parkinson syndrome (PS) by using mass spectrometry (MS)-based brain proteomics.…Progressive supra nuclear palsy phenotype with idiopathic basal ganglia calcification
Objective: To present a rare case of progressive supra-nuclear gaze palsy (PSP) in a patient with idiopathic basal ganglia calcification in a patient with idiopathic…Dry eye in Parkinson’s disease: symptoms, consequences and treatment options
Objective: Dry eye is a common side effect of PD/PSP and easily manageable, yet its occurrence and debilitating ramifications are often unrecognized. The aim of…Preferred place of death (PPOD) in PD, PSP and MSA
Objective: To ascertain whether people with PD, PSP and MSA have a PPOD Background: Achieving a PPOD is felt to be an important factor in…Automated Quantitative MRI Biomarkers in Differentiation of Progressive Supranuclear Palsy and Multiple System Atrophy from Parkinson Disease
Objective: To explore the relative merits of automated MRI-based volumetric measures over visual assessment in the differential diagnosis of Parkinson's disease (PD), parkinsonian variant of…Cerebellar transcranial magnetic stimulation with neuronavigation for postural instability in PSP
Objective: We created a TMS protocol for paired-pulse cerebellar-M1 stimulation and repetitive cerebellar stimulation to augment cerebellar-brain inhibition and reduce postural instability in progressive supranuclear…Exploratory Analysis of Electrocortical Signal Complexity in Patients with Progressive Supranuclear Palsy and Corticobasal Degeneration
Objective: We evaluated self-similarity of electrocortical activity as expression of brain signal complexity in patients clinically affected by Progressive Supranuclear Palsy (PSP) and Corticobasal Degeneration…
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