Decline in the midbrain-to-pons ratio over one year can support the differentiation between PSP and IPD
Objective: The midbrain-to-pons ratio (MTPR) is considered as an important diagnostic biomarker to differentiate between progressive supranuclear palsy (PSP) and idiopathic Parkinson’s disease (IPD). Here,…Diagnostic accuracy of MR planimetry in clinically unclassifiable parkinsonism
Objective: To determine diagnostic accuracy of P/M, MRPI, and new indices termed P/M2.0 and MRPI2.0 (multiplying P/M and MRPI by third ventricle width/frontal horns width…Niemann-Pick Type C Presenting as Progressive Supranuclear Palsy
Objective: We report a very old patient who presented the clinical features of progressive supranuclear palsy (PSP) including supranuclear vertical gaze palsy with prominent cerebellar…Progressive supranuclear palsy: Common metabolic pattern in different variants
Objective: To define and cross-validate the brain glucose metabolic abnormalities in patients with a diagnosis of different PSP variants. Background: It remains unclear whether the supportive…The severity and distribution of tau pathology distinguish corticobasal degeneration and progressive supranuclear palsy
Objective: To elucidate whether the severity and distribution of tau pathology reflect the clinical presentations in progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD). Background:…Gait and motion analysis in Progressive Supranuclear Palsy
Objective: Evaluate gait abnormalities in progressive supranuclear palsy (PSP) with three-dimensional motion analysis. Background: PSP is associated with complex, disabling gait and balance abnormalities that…Can we stage tau pathology in PSP?
Objective: To evaluate distribution pattern of tau pathology in different PSP clinical subtypes and develop a staging system. Background: Progressive supranuclear palsy (PSP) is a…Identification and characterization of anti-prionic compounds that disassemble Tau prions as a novel therapeutic approach for tauopathies
Objective: Stabilization of monomeric Tau protein by transient and high-affinity binding ligands is a novel and highly innovative anti-prionic treatment strategy for tauopathies. Background: Tauopathies…Successful treatment of incessant purposeless groaning in Progressive Supranuclear Palsy with Pimozide
Objective: Evaluation of therapeutic options for a patient of Progressive Supranuclear Palsy (PSP) presenting with incessant purposeless groaning. Background: PSP is a neurodegenerative disorder characterized…Mass spectrometry-based proteomics brain analysis to distinguish between Parkinson syndromes
Objective: To address the gap existing during clinical diagnosis in differentiating among various forms of Parkinson syndrome (PS) by using mass spectrometry (MS)-based brain proteomics.…
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