Role of florzolotau (18F) positron emission tomography in the diagnosis and clinical management of progressive supranuclear palsy: a real-world study
Objective: This study aimed to evaluate the diagnostic utility of florzolotau (18F) positron emission tomography (PET) and its impact on therapeutic decision-making in patients with…Comparison of Regional Perfusion Patterns in Clinical Subtypes of PSP and CBD: Dual Phase [¹⁸F]FP CIT PET Study
Objective: To investigate the regional perfusion patterns using PET imaging across various clinical subtypes of PSP and CBD. Background: On MRI, PSP typically shows midbrain…REM Sleep Behaviour Disorder (RBD) and its relation to Non-motor Symptoms in Progressive Supranuclear Palsy(PSP).
Objective: To examine the frequency of RBD in PSP and its associations with other non-motor symptoms. Background: RBD once considered rare in PSP, is now…Clinical and Multimodal Biomarker Profiles in Progressive Supranuclear Palsy: The PSPNI Cohort Study in China
Objective: To present an overview of the Progressive Supranuclear Palsy Neuroimage Initiative (PSPNI) from China. Background: Progressive supranuclear palsy (PSP) is a rare neurodegenerative disease…Volumetric Imaging Diagnostic Tool to Differentiate Progressive Supranuclear Palsy from Parkinson’s Disease using Artificial Intelligence
Objective: To develop and evaluate a novel MRI-based volumetric diagnostic index using artificial intelligence–driven segmentation for differentiating progressive supranuclear palsy (PSP) from Parkinson’s disease (PD).…Atypical Parkinson: what can an outpatient Voice and Swallowing Clinic offer to patients
Objective: To examine the effectiveness of an Outpatient Voice and Swallowing Clinic in a tertiary referral centre for the management of swallowing of patients with…Phenotypic Evolution from Nonfluent PPA to PSP
Objective: Progressive Supranuclear Palsy (PSP) and Nonfluent Primary Progressive Aphasia (nfvPPA) are clinicopathological entities within the 4-repeat tauopathy (4R tauopathy) spectrum. Increasing evidence suggests that…MobilityAPP: A randomized-controlled trial evaluating gait-focused physiotherapy in Parkinson’s disease and atypical parkinsonian syndromes
Objective: Effect on gait and balance of gait-focused physiotherapy compared to standard-of-care physiotherapy in patients with MSA, PSP and PD. Background: Physiotherapy is a crucial element…Early Overlap of Corticobasal Syndrome and Richardson Syndrome in Corticobasal Degeneration: Evidence from 252 Autopsy-Confirmed Cases
Objective: This study aimed to identify early clinical phenotypes of corticobasal degeneration (CBD) using unsupervised analysis of a large clinicopathologic dataset. Background: Early diagnosis of…QSM-Based Substantia Nigra Volumetry Improves Differentiation of Progressive Supranuclear Palsy from Parkinson’s Disease and Multiple System Atrophy
Objective: To evaluate whether quantitative susceptibility mapping (QSM)-based substantia nigra (SN) volumetry improves differentiation of progressive supranuclear palsy (PSP) from Parkinson’s disease (PD) and multiple…
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