A Novel Case of Persistent Singing in Progressive Supranuclear Palsy
Objective: To present a unique case of a person with progressive supranuclear palsy (PSP) who developed persistent singing, and review the relevant literature. Background: Persistent…Cerebellar Variant of Progressive Supranuclear Palsy: First Case Report from Peru
Objective: To describethe clinical and neuroimaging features of a patient with the cerebellar variant of Progressive Supranuclear Palsy (PSP-C) Background: Progressive supranuclear palsy (PSP)is a…Sex Differences in Vascular Burden, Neurodegeneration, and Clinical Progression in Progressive Supranuclear Palsy Richardson Syndrome
Objective: To examine sex differences in cardiovascular risk, white matter hyperintensities (WMH), and neurodegeneration, and to determine their relationship with clinical progression in progressive supranuclear…Insights on the Groaning Phenomenon from a Large Asian Progressive Supranuclear Palsy Cohort
Objective: We investigated the frequency and phenomenology of groaning in progressive supranuclear palsy (PSP), and its association with disease parameters and caregiver burden. Background: “Purposeless”…Ferritin as a factor in the examination of Parkinson’s disease and Progressive Supranuclear Palsy
Objective: The goal of this study is to analyze the possible significance of serum ferritin levels in the examination of Parkinson’s disease (PD) and Progressive…Evidence of Systemic and Neuro-Inflammation in Progressive Supranuclear Palsy: Insight from an Imaging-Inflammation Study
Objective: To investigate the role of Th17 pathway in systemic and central inflammation in PSP and to identify signatures of inflammation-induced neurodegeneration in PSP. Background:…Molecular Profiling of Brain-Derived Extracellular Vesicles and Fluid Biomarkers in Parkinsonism: Distinct Signatures and Clinical Correlates in Progressive Supranuclear Palsy
Objective: (1) To validate serum-based enrichment of neuronal (L1CAM+) and microglial (TMEM119+) EVs in PSP; (2) to characterize α-synuclein, tau, and inflammatory/autophagic mediators in EVs…Systemic Inflammation and Cerebral Small Vessel Disease in Progressive Supranuclear Palsy
Objective: To assess the cerebral small vessel disease (CSVD) burden in progressive supranuclear palsy (PSP) and examine the relationships among peripheral inflammatory markers, CSVD imaging…Coupling of Cholinergic and Dopaminergic Terminal Loss in Progressive Supranuclear Palsy: A Multimodal [18F]FEOBV and [11C]PE2I Study
Objective: To describe the relationships between dopaminergic and cholinergic terminal deficits in Progressive Supranuclear Palsy (PSP) relative to age-matched Normal controls (NC). Background: There is…Plasma Proteomics in PSP
Objective: We implemented an unbiased proximity extension proteomics assay to identify novel plasma PSP biomarkers. Background: Blood-based biomarkers can help to support non-invasive early diagnosis…
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