Results of a Phase 1, Single Ascending Dose, Placebo-Controlled Study of ABBV-8E12 in Patients with Progressive Supranuclear Palsy and Phase 2 Study Design
Objective: To present the results of a phase 1 study of ABBV-8E12 in subjects with Progressive Supranuclear Palsy (PSP) and design of a phase 2…Reversible progressive supranuclear palsy-mimic induced by risperidone
Objective: To report a patient who presented with a progressive supranuclear palsy (PSP)-like syndrome while receiving risperidone that disappeared after drug withdrawal. Background: Drugs that…The basal ganglia muscarine receptors impairment in progressive supranuclear palsy
Objective: To measure muscarinic M2 and M4 receptors in the basal ganglia in PSP. Background: Progressive supranuclear palsy is a nuerodegenerative Parkinson's plus syndrome. This…Atypical Parkinsonian disorders: Insights for a differential diagnosis through the analysis of oculomotor profile in MSA, PSP and CBD patients
Objective: To determine peculiar changes in oculomotor profile that may help in distinguishing atypical parkinsonism with overlapping clinical features. Background: Atypical Parkinsonian disorders (APDs) include…Sleep disorders in progressive supranuclear palsy
Objective: Assessment of incidence of insomnia in PSP, its connection with motor, neuropsychological and behavior disorders, evaluation of impact on the quality of life. Background:…Creative thinking and parkinsonism: Preliminary clinical data on the role of frontal area
Objective: To evaluate divergent thinking (DT) by means of Abbreviated Torrance Test for Adults (ATTA) in Parkinsonism (PKS) with different deficit in cognitive functions. Background:…THK-5351 tau-tracer uptake in patients with clinically diagnosed progressive supranuclear palsy
Objective: The objective of our study is to investigate characteristics of THK-5351 binding in patients with clinically diagnosed progressive supranuclear palsy (PSP) and correlate tau-tracer…Incidence of dystonia in patients with progressive supranuclear palsy
Objective: To study the frequency of dystonic symptoms in progressive supranuclear palsy (PSP). Background: Progressive supranuclear palsy (PSP) is an uncommon brain disorder that affects…Cognitive functioning in Parkinson’s disease and Parkinson plus syndrome
Objective: Our study aimed to investigate and compare the cognitive functioning in PD and PPS. Background: Parkinson[s] disease (PD) is now known to be associated…Assessment of subclinical cerebellar involvement in progressive supranuclear palsy using SUIT based volumetric analysis
Objective: To explore the pattern of cerebellar atrophy if any, in patients with Progressive Supranuclear Palsy (PSP) using the SUIT (Spatially Unbiased atlas template for…
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