SNCA hypomethylation in rapid eye movement sleep behavior disorder is a potential biomarker for Parkinson’s disease
Objective: We aimed to explore whether there were different distributions of α-synuclein at a genetic and/or protein level in patients with iRBD. Background: α-Synuclein has been related to…White matter abnormalities and its relation to cognitive impairment in isolated Rapid Eye Movement sleep behavior disorder
Objective: To study white matter (WM) abnormalities and global cortical atrophy in isolated rapid eye movement sleep behavior disorder (IRBD) patients and its relation to cognitive…The short- and long-term outcomes of STN DBS in PD patients with or without RBD
Objective: We aimed to assess the short- and long-term outcomes of bilateral subthalamic (STN) deep brain stimulation (DBS) including the motor performance and quality of…Progression of cortical thinning and neuropsychological decline in isolated Rapid Eye Movement sleep behavior disorder
Objective: We aimed to investigate the progression over time of cortical thickness and cognitive functions in isolated REM-sleep behaviour disorder (IRBD) compared to healthy controls (HC).…Gait and turning alterations in idiopathic REM sleep behavioral disorder and early Parkinson’s disease: a cross-sectional study with mobile health technology
Objective: The aim of the study was investigate the differences in performances of gait and turning under supervised conditions in healthy controls (HC), idiopathic REM…Multimodal model of Parkinson’s disease highlights differences in progression profiles of RBD patients
Objective: To compare subgroups of patients with Parkinson’s disease (PD) with and without rapid eye movement sleep behavior disorders (RBD), in terms of progression speed,…Slow Motion Analysis of Repetitive Tapping (SMART) test: a new means to assess bradykinesia
Objective: To develop a quantitative and objective tool to track repetitive tapping movement (RTM) using a slow motion capture and compare patients with Parkinson’s disease…The relationship between REM sleep behavior disorder and cognitive impairment in drug-naïve Parkinson’s disease
Objective: We aim to compare the cognitive performances of drug-naïve PD patients who had RBD (PD-RBD) to PD patients without RBD (PD-NRBD) and healthy controls.…Association between SNCA and clinical phenotypes of Parkinson’s disease in southern Chinese
Objective: The aim was to investigate the association between SNCA and clinical phenotypes of Parkinson’s disease (PD) in southern Chinese. Background: SNCA gene plays an…Dual hit model of Parkinson’s disease propagation using MRI biomarkers and partial least squares path modeling
Objective: This study aimed using multimodal MRI to test two models of Parkinson’s disease propagation and investigated how the models were influenced by the presence…
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