The Impact of Insomnia and Sleep Fragmentation on Quality of Life and Neuropsychiatric Outcomes in Restless Legs Syndrome
Objective: To quantify the prevalence of insomnia, sleep architecture disruption, and their cascading impacts on emotional well-being and overall quality of life in patients with…Identifying Differential DNA Methylation Pathways in Parkinson’s Disease and REM Sleep Behavior Disorder
Objective: To investigate differential methylation patterns of cell-free DNA (cfDNA) between Parkinson’s Disease (PD), REM Sleep Behavior Disorder (RBD), and Healthy Control (HC) groups. Background:…Circadian Rhythms: Role in Movement Disorders and associated Sleep Disturbances.
Objective: Understanding the role of circadian rhythm in movement disorder and associated sleep disturbances. Background: Dopamine and other neurotransmitters(NTs) follow a circadian rhythm. NTs have…Exploring Retrospectively the Predisposing Factors of Sleep Disorders in Parkinson’s Disease.
Objective: Identify the predisposing or exacerbating factors of sleep disorders in Parkinson's disease, and examine their association with levodopa treatment. Background: Parkinson's disease (PD) is…Racial Disparities in Hospitalization Characteristics among Native Hawaiians, Pacific Islanders and Asian American Subgroups with Restless Legs Syndrome
Objective: To determine if patient characteristics differ among Native Hawaiians/Pacific Islanders (NHPI), Asian American (AA) subgroups, and Whites who were hospitalized with Restless Leg Syndrome…Epigenetic clock acceleration is linked to earlier onset and phenoconvertion of Rapid-eye-movement sleep behavior disorder
Objective: In the current study, we aim to evaluate whether Rapid-eye-movement sleep behavior disorder (RBD) age-at-onset and age-at-phenoconversion are associated with DNA methylation-age acceleration (DNAm-AA).…National Luxembourg Sleep Study: An enriched, at risk, prodromal Parkinson’s Disease cohort
Objective: To identify a cognitively intact enriched cohort of people with isolated rapid eye movement (iREM) sleep behaviour disorder (iRBD) and hyposmia, at risk of…Relevance of amyloid deposition for REM sleep behavior disorder in Parkinson’s disease
Objective: In this study, we aimed to investigate the relationship between regional [18F]florbetaben PET binding to amyloid-β (Aβ) and REM sleep behavior disorder (RBD) in…The relationship between sleep and Parkinson’s disease progression: A Mendelian Randomization study
Objective: The objective of the study was to determine the causality between sleep disorders and progression of motor and cognitive endpoints of Parkinson’s disease. Background:…Biomarkers of idiopathic REM sleep behavior disorder versus RBD within narcolepsy
Objective: We compared iRBD versus secondary RBD due to narcolepsy, searching for discriminating clinical, neurophysiological and pathological biomarkers. Background: Idiopathic REM sleep behavior disorder (iRBD)…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.