Epigenetic clock acceleration is linked to earlier onset and phenoconvertion of Rapid-eye-movement sleep behavior disorder
Objective: In the current study, we aim to evaluate whether Rapid-eye-movement sleep behavior disorder (RBD) age-at-onset and age-at-phenoconversion are associated with DNA methylation-age acceleration (DNAm-AA).…National Luxembourg Sleep Study: An enriched, at risk, prodromal Parkinson’s Disease cohort
Objective: To identify a cognitively intact enriched cohort of people with isolated rapid eye movement (iREM) sleep behaviour disorder (iRBD) and hyposmia, at risk of…Relevance of amyloid deposition for REM sleep behavior disorder in Parkinson’s disease
Objective: In this study, we aimed to investigate the relationship between regional [18F]florbetaben PET binding to amyloid-β (Aβ) and REM sleep behavior disorder (RBD) in…The relationship between sleep and Parkinson’s disease progression: A Mendelian Randomization study
Objective: The objective of the study was to determine the causality between sleep disorders and progression of motor and cognitive endpoints of Parkinson’s disease. Background:…Biomarkers of idiopathic REM sleep behavior disorder versus RBD within narcolepsy
Objective: We compared iRBD versus secondary RBD due to narcolepsy, searching for discriminating clinical, neurophysiological and pathological biomarkers. Background: Idiopathic REM sleep behavior disorder (iRBD)…Improved sleep structure after cerebrospinal fluid shunting for idiopathic normal pressure hydrocephalus
Objective: To elucidate the effect of cerebrospinal fluid (CSF) shunt surgery for the sleep of idiopathic normal pressure hydrocephalus. Background: Sleep Disturbance in Parkinson’s disease…Sleep Abnormalities in patients with Parkinson’s disease having REM sleep behaviour disorder with and without Psychosis
Objective: To study the polysomnographic changes in patients of Parkinson’s disease with or without psychosis and evaluate any microarchitecture and microarchitecture changes. Background: Parkinson’s disease…Baseline risk factors of insomnia symptoms after five years of follow-up: a population-based cohort of incident Parkinson’s disease
Objective: To investigate baseline risk factors of insomnia symptoms after five years of follow-up, on average, in a population-based study of Parkinson’s disease (PD). Background:…Hypothalamic volume loss is associated with reduced melatonin output in Parkinson’s disease
Objective: Our aim was to compare hypothalamic volumes in PD patients with matched controls, and determine whether volume loss correlated with reduced melatonin output in…Nighttime sleep problems in patients with Parkinson’s disease: Risk factors and longitudinal associations
Objective: The aim of this longitudinal study is to examine which factors are associated with longitudinal changes and future occurrence of nighttime sleep problems (NSP)…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.