Unilateral focused ultrasound subthalamotomy in early Parkinson’s disease: randomized-controlled trial protocol
Objective: To describe the protocol of a multicenter, prospective, randomized controlled trial (EarlyFocus II) which evaluates the efficacy and safety of unilateral magnetic resonance-guided focused…Phase I randomized, double-blind study to evaluate feasibility, safety, and clinical responses of implanting autologous peripheral nerve tissue into the nucleus basalis of Meynert or substantia nigra for non-motor or motor symptoms in patients with Parkinson’s disease undergoing DBS surgery (STAR) Trial
Objective: To evaluate the feasibility, safety, and clinical responses of bilateral delivery, at the time of deep brain stimulation (DBS) surgery, of autologous peripheral nerve…Automated Image-Guided Programming Algorithm Supports Clinicians During DBS Programming for Parkinson’s Disease Patients
Objective: To assess clinical outcomes of an acute automated image-guided programming (aIGP) algorithm in PD patients implanted with a deep brain stimulation (DBS) system. Background:…Deep Brain Stimulation and Lesional Surgery in Parkinson’s Disease: Our Experience in Santa Cruz de la Sierra, Bolivia
Objective: To evaluate the outcomes and complications of deep brain stimulation (DBS) and ablative surgery in patients with Parkinson’s disease (PD) in our center. Background:…Optimization of Adaptive Deep Brain Stimulation Settings in Patients with Parkinson’s Disease
Objective: To evaluate the specific programming parameters of adaptive deep brain stimulation (aDBS) in Parkinson’s disease (PD) and identify the most effective settings for optimizing…Eight-Year Outcome of Focused Ultrasound Thalamotomy in Tremor Dominant Parkinson’s Disease Patients
Objective: To assess the 8-year outcome of unilateral MRI guided focused ultrasound (MRgFUS) ventral intermediate nucleus thalamotomy in tremor dominant Parkinson's disease (TDPD) patients, with…Intraoperative Local Field Potentials and Selection of Deep Brain Stimulation Programming Contacts in Patients with Essential Tremor and Parkinson’s Disease
Objective: To report correlations of intraoperative local field potentials (LFPs) with longitudinal selection of optimal deep brain stimulation (DBS) programming contacts in patients with essential…12-month long-term outcomes of adaptive DBS using LFP sensing technology
Objective: The aim of this study was to clarify the 12-month long-term outcome of Parkinson’s disease (PD) patients receiving adaptive DBS therapy. Background: During the…Extended long-term follow-up focused ultrasound subthalamotomy in Parkinson´s disease: five-year prospective experience
Objective: To assess the safety and efficacy of unilateral focused ultrasound subthalamotomy (FUS-STN) for Parkinson`s disease (PD) 5 years after treatment. Background: FUS-STN improves cardinal…Pharmacological neuromodulation with intracerebroventricular administration of anaerobic dopamine for Parkinson’s disease
Objective: To assess the continuous intracerebroventricular (i.c.v.) of A-dopamine in patients with a telemetry-controlled intra-abdominal pump system connected to a subcutaneous catheter implanted through the…
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