Sweetspot analysis of Deep Brain Stimulation in Parkinson´s disease: Beyond the subthalamic nucleus?
Objective: To study the relationships between clinical response and leads location -in a cohort of Parkinson’s disease (PD) patients and deep brain stimulation of subthalamic…Apathy and Volume of Tissue Activated (VTA) following Bilateral Subthalamic Deep Brain Stimulation for Parkinson’s Disease: The INTREPID Cohort
Objective: To determine frequency and/or predictors of improvement or worsening of apathy, we evaluated this behavior among those who received bilateral subthalamic deep brain stimulation…Phase-amplitude coupling between beta power and high frequency oscillations as a sensitive marker of parkinsonian state.
Objective: The aim of this work was to study the potential clinical usefulness of the phase-amplitude coupling (PAC) between beta power and high frequency oscillations (HFO´s).…Programming Time and the Use of a Visualization Tool for DBS Programming of a Multiple-Source, Constant-Current System
Objective: To describe utilization of image-guided programming for use as a deep brain stimulation (DBS) planning tool during initial device programming in a cohort of…Mechanisms and Consequences of Weight Gain After Deep Brain Stimulation of the Subthalamic Nucleus in Patients with Parkinson’s Disease
Objective: To identify stimulation-dependent effects of deep brain stimulation (DBS) on body weight and energy metabolism depending on the electrode position within the subthalamic nucleus…Mania induced by STN-DBS is related to the stimulation of the ventromedial subthalamic nucleus in Parkinson’s disease: a prospective study
Objective: To investigate the incidence, risk and etiological factors, clinical management and consequences of mania following subthalamic nucleus deep brain stimulation (STN-DBS) in Parkinson’s disease…Machine learning supervised classification study for Parkinson`s disease progression through graph-based feature selection method
Objective: The model helps neuro physicians/ neurologists to improve the PD symptoms, or therapeutic-treatment planning-procedures. Background: Artificial intelligence-based machine learning (AI-ML) supervised classification systems have…Thalamic white matter macrostructure and subnuclei volumes in Parkinson’s disease depression
Objective: To investigate thalamic subnuclei volume and macrostructural white matter changes in Parkinson’s disease (PD) depression. Background: Depression is a common neuropsychiatric feature of Parkinson’s…Subthalamic tremor-related oscillatory neurons play a role in the generation of Parkinson’s tremor
Objective: To explore whether subthalamic tremor-related oscillatory neurons is involved in the generation of Parkinson’s tremor. Background: Both the basal ganglia and cerebello-thalamo-cortical circuits appear…Monitoring local field potentials recorded after implant surgery from deep brain stimulation leads in the subthalamic nucleus using a sheep animal model
Objective: The objective of this study was to track if/how local field potentials (LFP) change characteristics over the first few days after implantation of a…
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