Preoperative motor deficits and depressive symptoms predict quality of life in patients with Parkinson’s disease at different time points after surgery for subthalamic stimulation.
Objective: This retrospective study explored whether preoperative motor, cognitive, and affective parameters predict QoL and QoL components at 6 and 12 months after STN-DBS surgery.…Representation of movement repertoire in subthalamic neural circuits using a markerless 3D behavioral tracking system.
Objective: This study aimed to investigate the spatiotemporal encoding of neurons in the subthalamic nucleus using a mouse model. Background: The subthalamic nucleus is a…Patterns of subthalamic synchronized oscillatory activity associated with parkinsonian subtypes
Objective: To explore whether patterns of synchronized subthalamic oscillatory neurons are involved in generating parkinsonian subtypes. Background: The pathophysiology for parkinsonian subtypes is unclear. Both…Deep brain stimulation enhances movement velocity during spiral drawing in Parkinson’s disease
Objective: To investigate the relationship between subthalamic beta activity and hand drawing characteristics. Background: Parkinson’s disease (PD) affects various motor functions such as handwriting, walking,…Effects of Subthalamic Nucleus Deep Brain Stimulation on Phase Amplitude Coupling in Parkinson’s disease
Objective: To investigate the effects of deep brain stimulation (DBS) on neural activity in patients with Parkinson's disease (PD). Specifically, to assess the effects of…Real-World Outcomes with Directional Deep Brain Stimulation (DBS) Systems: Awake versus Asleep Lead Placement
Objective: In this report, we compared real-world outcomes of Parkinson's disease (PD) patients using Deep Brain Stimulation (DBS) Systems based on patients being awake or…SAFE-DBS – A monocentric, randomised, blind evaluation of safinamide in the perioperative period in Parkinsonian patients with deep brain stimulation
Objective: This monocentric, randomised, blind study is designed to evaluate the effect of safinamide on motor and neuropsychiatric symptoms in the 3 month perioperative period…Characteristics of cases in which stimulation was programmed for multiple targets in deep brain stimulation therapy for Parkinson’s disease.
Objective: To clarify the the clinical background of Parkinson's disease patients with DBS who received multiple stimulus targets. Background: Deep brain stimulation (DBS) is an…Predicting motor outcome and quality of life after subthalamic DBS for Parkinson’s Disease: the role of standard screening measures and wearable-data
Objective: To evaluate the utility of universal components incorporated in the DBS screening, complemented by a wearable sensor, to predict motor outcomes and Quality of…local field potential differences in stn subregion during performance of a conflict task in humans with parkinson’s disease
Objective: Examine dorsal and ventral STN subregion's roles in motor conflict with intraoperative recordings during the implantation of a DBS device in Parkinson’s disease (PD)…
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