Deep brain stimulation impacts functional brain connectivity in Parkinson’s disease.
Objective: Deep-brain stimulation (DBS) became a successful method to treat Parkinson’s disease (PD), particularly with stimulating the subthalamic nucleus (STN-DBS), although the precise mechanisms mediating…Tremor characteristics differentially respond to levodopa and subthalamic nucleus deep brain stimulation in Parkinson’s disease
Objective: To identify factors predictive of responsiveness of tremor to levodopa and STN-DBS. Background: Tremor in Parkinson’s disease (PD) is phenotypically variable and has an…Directional deep brain stimulation therapy in the long term
Objective: To describe our long-term clinical experience with directional deep brain stimulation (d-DBS) in patients with advanced Parkinson’s disease (PD) who have been implanted with…Effects of GBA1 mutations and STN-DBS on response inhibition in Parkinson’s disease
Objective: To determine specific pattern of cognitive dysfunction in Parkinson’s disease (PD) patients who are glucocerebrosidase mutation carriers (PD-GBA1) compared with non-mutation carriers with and…Clinical accuracy of Medtronic’s Percept built in longevity estimate algorithm following device exchange.
Objective: To examine the accuracy of Medtronic’s Percept built in device longevity estimate. Background: In June of 2020 Medtronic received FDA approval for its Percept…Impulse Control Disorders Following Bilateral Subthalamic Deep Brain Stimulation for Parkinson’s Disease: The INTREPID Randomized Controlled Trial
Objective: To assess the frequency and outcomes of impulsivity in study participants receiving bilateral subthalamic deep brain stimulation (STN-DBS) for the treatment of Parkinson’s Disease…High-beta Oscillations Predict Outcome of Subthalamic Deep Brain Stimulation in Parkinson’s Disease
Objective: We evaluated whether low-β and high-β band activity recorded from the subthalamic nucleus (STN) region predicts efficacy of deep brain stimulation (DBS) in Parkinson's…Real-World Deep Brain Stimulation Outcomes Using DBS Systems with Directionality and Multiple Independent Current Control
Objective: We report clinical outcomes associated with the use of Deep Brain Stimulation (DBS) systems capable of directionality and Multiple Independent Current Control (MICC). Background:…Long-term non-motor and motor outcome after subthalamic stimulation in Parkinson’s disease
Objective: The primary objective of this study was to document the evolution of independence in activities of daily living in people with Parkinson’s disease treated…Subthalamic beta bursts reflect the continuous stochastic fluctuations of ongoing oscillations in Parkinson’s disease
Objective: To test whether subthalamic beta bursts in Parkinson’s disease reflect the continuous stochastic fluctuations of an oscillatory random process. Background: Subthalamic beta oscillations in…
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