MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Synucleinopathies"

  • 2024 International Congress

    Plasma Biomarkers of Alzheimer’s Pathology Identify Prodromal Dementia with Lewy bodies

    A. Delva, A. Pelletier, E. Sommerville, J. Montplaisir, J. Gagnon, G. Kollmorgen, T. Kam-Thong, T. Kustermann, V. Machado, Z. Gan-Or, R. Postuma (Montreal, Canada)

    Objective: To determine whether plasma biomarkers of Alzheimer’s disease (AD) pathology can predict phenoconversion from idiopathic/isolated REM sleep behavior disorder (iRBD) to dementia with Lewy…
  • 2024 International Congress

    Common Genetic Variation Associated with Parkinson’s Disease Biological Measures

    EN. Somerville, K. Senkevich, M. Ta, E. Yu, H. Iwaki, Z. Gan-Or (Montreal, Canada)

    Objective: To identify common genetic variants associated with biological measures that have been implicated in Parkinson’s disease and related synucleinopathies. Background: Alpha synucleinopathies, mainly including…
  • 2024 International Congress

    Sex Differences for Regional Lewy Body Pathology in Pathologically-Defined Lewy Body Dementia

    E. Bayram, D. Coughlin, S. Koga, I. Litvan, D. Dickson (La Jolla, USA)

    Objective: To investigate sex differences for regional Lewy body (LB) pathology burden, and regional LB pathology association with clinical diagnosis across people with a high…
  • 2024 International Congress

    Longitudinal Gait Speed Analysis at Prodromal and Early Stage of Parkinson’s Disease

    S. Sambin, M. Houot, F. Khoury, G. Mangone, L-L. Mariani, I. Arnulf, S. Lehericy, M. Vidailhet, J-C. Corvol (Paris, France)

    Objective: We aimed at exploring gait speed (GS) as a potential biomarker of disease evolution in early stages of PD with three objectives. 1- To…
  • 2024 International Congress

    Early Dementia with Lewy Bodies and Parkinson’s Disease with RBD: two faces of the same coin?

    B. Orso, P. Mattioli, F. Famà, F. Massa, M. Pardini, A. Brugnolo, N. Girtler, S. Raffa, L. Sofia, S. Morbelli, D. Arnaldi (Genoa, Italy)

    Objective: To describe clinical and imaging differences in de novo PD with and without REM sleep Behaviour Disorder (dnPDRBD – de novo PD) and de…
  • 2024 International Congress

    Clinical Utility of Synuclein Skin Biopsy in the Initial Diagnosis and Evaluation of Parkinsonian Disorders

    J. Isaacson, R. Freeman, C. Gibbons, A. Alshehri (Boston, USA)

    Objective: To determine the clinical utility of phosphorylated alpha-synuclein (P-SYN) within skin biopsies in diagnostic and management decisions. Background: The initial diagnosis of Parkinson’s Disease…
  • 2024 International Congress

    Prevalence of Non-Motor Symptoms in Patients with Parkinson Disease in a Tertiary Hospital in Santiago, Chile.

    M. Sánchez, V. Rosado, C. Montalva, P. Salles, J. Fuentes, P. Chaná (Santiago, Chile)

    Objective: Objective:Determine the prevalence of NMS in patients with Parkinson disease attending the Hospital San Juan de Dios Neurology Clinic. Background: Background:Parkinson disease (PD) is…
  • 2023 International Congress

    Transferrin as a possible CSF biomarker in neurodegenerative proteinopathies

    K. Mensikova, P. Kanovsky, K. Klicova, D. Konickova, S. Kurcova, M. Nevrly, P. Otruba, Z. Grambalova, M. Kaiserova, J. Zapletalova (Olomouc, Czech Republic)

    Objective: The aim of this study was to determine whether cerebrospinal fluid (CSF) levels of transferrin differ between patients with Parkinson´s disease (PD), multiple system…
  • 2023 International Congress

    Exosomal α-synuclein in Multiple system atrophy and parkinson’s disease cause distinct synucleinopathies

    X. Chi, L. Kou, Y. Sun, Y. Xia, T. Wang (Wuhan, China)

    Objective: In this study, we investigated the differences in exosomal α-syn between MSA and PD patients. Background: Parkinson's disease (PD) and multiple system atrophy (MSA)…
  • 2023 International Congress

    An Analysis of Subgroups of Multiple System Atrophy Patients from Ampreloxetine Phase 3 Trials

    R. Freeman, I. Biaggioni, L. Norcliffe-Kaufmann, T. Guerin, R. Vickery, L. Manzanares, V. Iodice, M. Rudzińska-Bar, M. Pellecchia, H. Kaufmann (Boston, USA)

    Objective: To present results in the subset of patients with multiple system atrophy (MSA) and relevant MSA subgroups from two ampreloxetine phase 3 trials for…
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