Non-motor symptom burden is associated with thalamic atrophy in Parkinson’s disease
Objective: To investigate whether non-motor symptoms burden is associated with cortical and subcortical morphological changes in PD patients. Background: Non-motor symptoms are common aspects of…Dopamine reduces Parkinson’s tremor through increased thalamic inhibition
Objective: To identify cerebral mechanisms explaining the effects of dopamine on rest tremor in Parkinson's disease. Background: Resting tremor in Parkinson's disease is related to…Changes of brain structure and cognition in individuals with possible prodromal Parkinson’s disease
Objective: Investigating brain structure and cognition in healthy individuals with positive Parkinson's disease (PD) risk markers (hyposmia, increased hyperechogenic area of the substantia nigra). Background:…Increasing placebo response in Parkinson’s disease through apomorphine pre-conditioning
Objective: To see whether a placebo response requires pharmacological pre-conditioning with apomorphine. Background: Placebos have been found to affect the patient's brain in a number…Combined pallidal and thalamic stimulation for multifocal primary dystonia with prominent writers’ cramp
Objective: When a patient presents with both writer's cramp and other dystonic symptoms, it is unclear which target should be chosen. Multifocal DBS is a…Movement disorders in patients with Japanese encephalitis: Experience in a tertiary care hospital in north eastern region of India
Objective: Movement disorders in Japanese encephalitis is known, but under reported. In this study we tried to analyse the spectrum of movement disorders in patients…Effect of intra-striatal 6-OHDA lesion on extra-striatal structures in the mouse
Objective: Characterization of extra-striatal manifestations in the 6-hydroxydopamine (6-OHDA) Parkinson's disease (PD) animal model. Background: PD is a neurodegenerative disorder characterized by progressive loss of…Modulation of thalamocortical network dynamics via deep brain stimulation in humans with Tourette syndrome
Objective: To (1) investigate the impact on thalamocortical network dynamics in response to low frequency and high frequency deep brain stimulation and (2) uncover the…Single unit activity of medial thalamus during goal-directed motor and cognitive behavior in patients with cervical dystonia
Objective: To 1) study neuronal activity of medial thalamic nuclei (MD, CM-Pf) and its role in cognitive and motor human activity and 2) evaluate neuronal…
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