STOP-TIC Study: Strengthening Tourette Treatment Options using TMS to Improve CBIT, a randomized sham-controlled trial
Objective: To determine if accelerated repetitive transcranial magnetic stimulation (rTMS) administered prior to Comprehensive Behavioral Intervention for Tics (CBIT) will improve tics in Tourette Syndrome…Anterior Pallidal Stimulation for Severe Tourette Syndrome: Open Phase Outcomes
Objective: To present the open phase outcomes of a trial of anterior pallidal stimulation (antGPi DBS) on tic severity in patients with severe Tourette syndrome…Aversions as Triggers for Tic Exacerbations
Objective: We report three cases of Tourette syndrome wherein aversions were extreme triggers for tics. These mundane sensory stimuli provoked intense tic exacerbation. Background: Tic…Real-World Experiences with VMAT2 Inhibitors in Pediatric Hyperkinetic Movement Disorders
Objective: We review the real-world prescribing practices and patient experiences with VMAT2 inhibitors in children. Background: Vesicular monoamine transporter 2 (VMAT2) inhibitors are often prescribed…Efficacy of Clonidine for Tourette Syndrome: An Updated Meta-Analysis of Randomized Controlled Trials
Objective: To evaluate the efficacy of Clonidine in reducing tic severity and improving global clinical outcomes in patients with Tourette syndrome. Background: Tourette syndrome is a neurodevelopmental disorder…Dual Target Bi Pallidal Deep Brain Stimulation in Tourette Syndrome Deciphering Neurophysiology with Chronic Local Field Potential Recordings
Objective: To investigate the neurophysiological activity of dual-target bi-pallidal DBS in Tourette Syndrome (TS) patients using chronic local field potential (LFP) recordings in an outpatient…Safety and Tolerability of Ecopipam in Tourette Syndrome (TS) with Psychiatric Comorbidities.
Objective: Evaluate the effect of ecopipam in children and adolescents with TS on measures of attention deficit disorder (ADHD), anxiety disorders (ANX), obsessive-compulsive disorder (OCD)…Ecopipam does not adversely affect Metabolic Parameters in Pediatric Subjects with Tourette Syndrome: Results from a Phase 2b with 12-month Open Label Extension Study
Objective: Determine if ecopipam is associated with the emergence of clinical features suggestive of metabolic syndrome in pediatric subjects with Tourette Syndrome (TS) Background: Dopamine-2…Pregnancy in Dystonia or Tourette’s patients with DBS. Eleven New Cases and a Review of the Literature.
Objective: To review the available literature on pregnancy in patients who have received deep brain stimulation (DBS) for dystonia or Tourette’s syndrome (TS). Background: DBS…How Local Field Potencial could improve GPi Deep Brain Stimulation programming in Tourette`s Syndrome – Case Report
Objective: We report a case of a young woman with refractory severe TS treated with DBS on anterior globus pallidus internus. Background: The Tourette Syndrome…
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