STOP-TIC Study: Strengthening Tourette Treatment Options using TMS to Improve CBIT, a randomized sham-controlled trial
Objective: To determine if accelerated repetitive transcranial magnetic stimulation (rTMS) administered prior to Comprehensive Behavioral Intervention for Tics (CBIT) will improve tics in Tourette Syndrome…Anterior Pallidal Stimulation for Severe Tourette Syndrome: Open Phase Outcomes
Objective: To present the open phase outcomes of a trial of anterior pallidal stimulation (antGPi DBS) on tic severity in patients with severe Tourette syndrome…Aversions as Triggers for Tic Exacerbations
Objective: We report three cases of Tourette syndrome wherein aversions were extreme triggers for tics. These mundane sensory stimuli provoked intense tic exacerbation. Background: Tic…Real-World Experiences with VMAT2 Inhibitors in Pediatric Hyperkinetic Movement Disorders
Objective: We review the real-world prescribing practices and patient experiences with VMAT2 inhibitors in children. Background: Vesicular monoamine transporter 2 (VMAT2) inhibitors are often prescribed…Efficacy of Clonidine for Tourette Syndrome: An Updated Meta-Analysis of Randomized Controlled Trials
Objective: To evaluate the efficacy of Clonidine in reducing tic severity and improving global clinical outcomes in patients with Tourette syndrome. Background: Tourette syndrome is a neurodevelopmental disorder…Dual Target Bi Pallidal Deep Brain Stimulation in Tourette Syndrome Deciphering Neurophysiology with Chronic Local Field Potential Recordings
Objective: To investigate the neurophysiological activity of dual-target bi-pallidal DBS in Tourette Syndrome (TS) patients using chronic local field potential (LFP) recordings in an outpatient…Deep Brain Stimulation in Tourette Syndrome: Characteristics of Three Patients Pre and Post Implantation
Objective: To elucidate how deep brain stimulation (DBS) for Tourette’s syndrome (TS) impacts psychiatric comorbidities including attention-deficit/hyperactivity disorder (ADHD), obsessive-compulsive disorder (OCD), anxiety, and depression.…Effect of Ecopipam, a Selective Dopamine-1 Receptor Antagonist, on Tic Characteristics as Assessed by the YGTSS: Results from a Phase IIb Randomized, Double-blind, Placebo-controlled Clinical Trial in Tourette Syndrome
Objective: Assess the effect of ecopipam treatment on motor and phonic/vocal tic characteristics: number, frequency, intensity, complexity, and interference comprising the Yale Global Tic Severity…Randomized Controlled Trial of Supplementary Motor Area Transcranial Direct Current Stimulation in Tourette Syndrome
Objective: To investigate the effect of cathodal transcranial direct current stimulation (tDCS) over the supplementary motor area (SMA) on tic severity in Tourette syndrome (TS).…Gaps in Diagnosing and Treating Tic Disorders in Latin America: A Survey of Healthcare Workers
Objective: The objective of this study was to investigate the knowledge, treatment, and diagnosis pathways followed for Tic Disorders across Latin America. Background: Tic disorders…
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