White matter microstructural abnormalities in tremor dominant and non-tremor dominant Parkinson’s disease
Objective: To explore differences in white matter microstructural integrity in tremor dominant and non-tremor dominant Parkinson’s disease (PD) using tract based spatial statistics (TBSS). Background:…Can a “Shopping bag Tremor” be a Pre-diagnostic sign of Parkinson’s Disease?
Objective: To describe an unusual wrist tremor according the existing classification and discuss its aetiological diagnosis. Background: Although Parkinson’s disease (PD) is usually associated with…The pathophysiology of dystonic tremors and comparison with essential tremor
Objective: To explore the pathophysiology of dystonic tremors (DT) and comparison with essential tremor (ET). Background: The characteristics and mechanisms of tremor in dystonia are…Motor Networks in Tremor-Dominant Parkinson’s Disease. A resting-state functional MRI and diffusion tensor imaging analysis.
Objective: To investigate the integrity of cerebellothalamocortical circuit (CTCC) and basal ganglia-cortical loop (BGCL) connectivity in tremor-dominant PD (TD-PD) and compare with a group of akinetic-rigid…Functional connectivity within the cerebellum and brainstem in essential tremor patients– a tailored resting state fMRI approach
Objective: To better understand the pathophysiology of essential tremor (ET) by analysing brainstem and cerebellar neuronal circuitry activity with tailored fMRI resting state methods. Background:…Genetic analysis of DNA methylation and hydroxymethylation genes in Parkinson’s disease
Objective: To investigate the relationship between DNA methylation/hydroxymethylation genes and Parkinson’s disease (PD), we conducted genetic analysis in a relatively large Chinese population. Background: PD…Examining supplementary motor area-primary motor cortex connectivity in tremor-dominant Parkinson’s disease using a novel transcranial magnetic stimulation protocol to inform clinical practice
Objective: Objectives: (1) Measure test re-test reliability of dual-coil transcranial magnetic stimulation (TMS) measures of supplementary motor area-primary motor cortex connectivity (SMA-M1 connectivity). (2) Investigate…How cognitive effort increases Parkinson’s tremor – an effictive connectivity fMRI study
Objective: To elucidate the neural mechanisms underlying tremor amplification during cognitive effort. Background: Parkinson’s tremor is related to cerebral activity in both basal ganglia and…Cerebral differences between dopamine-resistant and dopamine-responsive Parkinson’s tremor
Objective: To disentangle the cerebral mechanisms underlying dopamine-resistant versus dopamine-responsive tremor in Parkinson’s disease. Background: Parkinson’s rest tremor is related to cerebral activity in both…Asymmetrical striatal dopamine transporter binding correlates with excess contralateral rest tremor
Objective: To investigate the relationship between striatal dopamine transporter binding and rest tremor. Background: In vivo dopamine transporter imaging is a useful tool for distinguishing…