Novel strategies based on sensory electrical stimulation to manage tremor in Parkinson’s disease. A pilot study.
Objective: Tremor can be a disabling motor symptom in patients with Parkinson´s disease (PD) and in some patients is refractory to medication. Here we present…Spinocerebellar ataxia 21 and phenotypic variability within a family
Objective: We describe four patients within a family who presented to our movement disorders centers for evaluation of various symptoms including unsteady gait, tremor, and…Analysis of tremor during grasp using ultrasound imaging.
Objective: To develop an ultrasound (US) image-based model for Essential and Parkinsonian tremor to be used in conjunction with functional electrical stimulation (FES) for tremor…A phase 2b, randomized, dose-response study of SAGE-324/BIIB124 for the treatment of essential tremor: KINETIC 2 trial in progress
Objective: The phase 2b KINETIC 2 trial is a double-blind, randomized, placebo-controlled, dose-response study designed to evaluate SAGE-324/BIIB124 (SAGE-324) for the treatment of patients with…Preclinical Characterization of Suvecaltamide for Essential Tremor
Objective: To characterize the in vitro T-type calcium (CaV3) channel target pharmacology and in vivo anti-tremor profile of suvecaltamide (JZP385, CX-8998). Background: CaV3 channels, a…Clinical effectiveness and economic impact of transcutaneous afferent patterned stimulation therapy for essential tremor in a real-world setting: protocol for a pragmatic trial
Objective: To determine the feasibility of delivery, clinical effectiveness, healthcare resource utilization (HCRU) and costs of transcutaneous afferent patterned stimulation (TAPS) therapy for the treatment…Intraoperative quantification of MDS-UPDRS tremor measurements using 3D accelerometry
Objective: This study focuses on translating parkinsonian tremor tests to an objective method to rate tremor severity using 3D accelerometry, that can be used during…Treatment of upper limb dystonic tremors: a retrospective study
Objective: Our study aimed to evaluate the clinical outcome of patients with upper-limb dystonic tremor (UL-DTs) treated at a tertiary hospital in London. Background: Tremor…Real-World Evidence Supports use of Transcutaneous Afferent Patterned Stimulation for Tremor Control in Veteran’s Affairs Essential Tremor Patients
Objective: This post-market analysis evaluated Transcutaneous Afferent Patterned Stimulation (TAPS) therapy for management of upper limb essential tremor in a cohort of Veteran Affairs (VA)…Randomised Controlled Trial Comparing Efficacy of Zonisamide 25 mg given in addition to standard treatment with standard treatment alone in Tremor dominant Parkinson’s Disease- A Pilot study.
Objective: To compare improvement in tremor at 12 weeks with Zonisamide given in a dose of 25 mg along with other ant- parkinsonian drugs as…
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