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Comprehensive analysis of non-motor symptoms and their association with quality of life in writer’s cramp

LY. Zhang, YB. Hou, J. Yang, B. Cao, HF. Shang (Chengdu, China)

Meeting: MDS Virtual Congress 2021

Abstract Number: 137

Keywords: Dystonia: Clinical features

Category: Dystonia: Epidemiology, Genetics, Phenomenology

Objective: The current study aimed to examine the frequency of non-motor symptoms and their association with quality of life in patients with writer’s cramp.

Background: Non-motor symptoms were common in patients with dystonia. However, limited studies have focused on writer’s cramp.

Method: A total of 61 patients with writer’s cramp were enrolled. Motor and non-motor symptoms were assessed using specific scales. Quality of life (QoL) was assessed using 36-item Short Form Health Survey. Multiple linear regression was used to analysis the association between non-motor symptoms and QoL.

Results: The most frequent non-motor symptoms in the current study were anxiety (47.5%) and depression symptoms (47.5%), followed by poor quality of sleep (41% in PSQI), EDS (29.5%), and fatigue (29.5%). We found that motor symptom had no association with QoL. Higher score of HDRS was associated with poor QoL as measured by PCS. Higher score of NRS, FSS, PSQI and HDRS were significant associated with poor QoL as measured by MCS.

Conclusion: Non-motor symptoms were prevalent in patients with writer’s cramp, with anxiety and depression symptoms as the most frequent. Pain, fatigue, poor quality of sleep, depression and anxiety symptoms were associated with poor QoL instead of motor symptom.

To cite this abstract in AMA style:

LY. Zhang, YB. Hou, J. Yang, B. Cao, HF. Shang. Comprehensive analysis of non-motor symptoms and their association with quality of life in writer’s cramp [abstract]. Mov Disord. 2021; 36 (suppl 1). https://www.mdsabstracts.org/abstract/comprehensive-analysis-of-non-motor-symptoms-and-their-association-with-quality-of-life-in-writers-cramp/. Accessed June 15, 2025.
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