Sphingosine-1-phosphate, motor severity and progression in Parkinson’s disease (MARK-PD)
Objective: We assessed the association of serum sphingosine-1-phosphate (S1P) levels with motor and cognitive symptoms in patients with Parkinson’s disease (PD). Background: Treatment with sphingosine-1-phosphate…The Prodromal PD study – multiple biomarkers for early diagnosis?
Objective: The study aims to deepen our understanding of the prodromal phase of Parkinson’s disease (PD) Background: At the time of PD diagnosis, nigrostriatal degeneration…GBA Mutation Accumulates Higher Alpha-Synuclein in Alpha-Synucleinopathies
Objective: To investigate whether post-translational modifications of α-synuclein will give rise to species that differ between PD cases with N370S GBA mutation and WT-PD. Background:…Comparative score on the MDS-UPDRS scale I, II and IV in patients with Parkinson disease with and without cardiovascular risk factors.
Objective: To find any relationship between cardiovascular risk factors such as diabetes mellitus, hypertension or both and worse state in patient with PD measured with…HbA1c correlates with motor and cognitive outcome scores in patients with Parkinson’s disease and type 2 diabetes.
Objective: The objective of this study was to investigate the relationship between glycated haemoglobin (HbA1c) levels in blood and clinical outcomes (MDS-UPDRS III, MDS-UPDRS IV,…Gut, nasal and oral dysbiosis in Parkinson’s disease
Objective: We aimed to identify the nasal, oral, and gut microbiota dysbiosis associated with the presence and clinical manifestations of Parkinson’s disease (PD) using 16s…Does the observation of an action inserted in an emotion-enriched context influence cortical excitability in patients with Parkinson’s disease?
Objective: To explore the effect induced by the observation of a grasping movement, inserted in different emotional contexts, on cortico-spinal excitability, in healthy people and…Decreased mesencephalic locomotor region activation explains loss of presynaptic inhibition during step initiation in people with Parkinson´s disease with freezing of gait
Objective: To investigate if decreased mesencephalic locomotor activation (MRL) activation during step initiation in an-event related fMRI protocol would explain the loss of presynaptic inhibition…Total cerebral small vessel score associated with Hoehn and Yahr stages in Parkinson’s disease
Objective: To evaluate the total cerebral small vessel disease (CSVD) score in patients with Parkinson’s disease at different stages and its related factors. Background: Parkinson’s…Evaluation of Acoustic Features of Speech for Monitoring Parkinson’s Disease Progression
Objective: Examine the temporal stability (i.e., repeatability) and sensitivity (i.e., change) of acoustic features of speech in people with Parkinson's Disease (PWP). Background: Voice and…
