MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2019 International Congress

    Smartphone software for home monitoring of motor symptoms in Parkinson’s disease – The CloudUPDRS Smartphone Software in Parkinson’s (CUSSP) study

    E. Menozzi, A. Jha, R. Oyekan, S. Schreglmann, A. Latorre, E. Mulroy, G. Roussos, C. Stamate, I. Daskalopoulos, J. Rothwell, K. Bhatia (London, United Kingdom)

    Objective: To determine the validity of smartphone software for objective monitoring of motor symptoms in patients with Parkinson’s disease (PD). Background: Although the MDS-Unified Parkinson’s…
  • 2019 International Congress

    GLYCOPAR – A randomized, placebo-controlled, 2-arm parallel-group superiority phase II study of glycopyrrolate for moderate-to-severe sialorrhea in Parkinson’s disease

    T. Mestre, E. Freitas, M. Lopez, A. Basndwah, L. de Oliveira, D. Al-Shorafat, Z. Alarfaz, H. Shinawi, S. Reddie, D. Mancini, J. Lui, D. Grimes, S. Fox (Ottawa, ON, Canada)

    Objective: To assess the 3-month efficacy and safety of glycopyrrolate for moderate-to-severe sialorrhea in Parkinson’s disease. Background: A systematic review reported that sialorrhea affects approximately…
  • 2019 International Congress

    Rivastigmine for visual hallucinations in Parkinson’s disease

    T. Mierlo, E. Foncke, R. Bie (Amsterdam, Netherlands)

    Objective: The aim of the study is to investigate whether early rivastigmine treatment of visual hallucinations in patients with Parkinson's disease delays the progression of…
  • 2019 International Congress

    Continuous circadian intracerebroventricular administration of anaerobic dopamine: A new therapeutic concept for Parkinson’s disease?

    C. Moreau, C. Laloux, C. Lachaud, E. Pioli, Q. Li, P. Pascal, L. Defebvre, R. Bordet, E. Bezard, M. Fisichella, D. Devos (Lille, France)

    Objective: We aim to overcome these challenges by demonstrating that continuous i.c.v. of Anaerobic-dopamine (A-dopamine,Patent #WO2015173258 A1) close to the striatum is a feasible and…
  • 2019 International Congress

    Evaluation of swallowing function by video-fluorography in patients with parkinsonism

    S. Nogawa, Y. Chin, H. Kanke, R. Kawamura, T. Nakayama, K. Tokuoka, T. Furukawa (Tokyo, Japan)

    Objective: The purpose of the present study is to investigate characteristic patterns of swallowing problems in each clinical entity of parkinsonism including Parkinson’s disease (PD)…
  • 2019 International Congress

    Impact of repeated oral administration of Opicapone on the plasma pharmacokinetics of levodopa

    M. Nomoto, A. Takeda, K. Iwai, A. Nishimura, N. Hattori (Ehime, Japan)

    Objective: To examine the inhibitory effect of COMT on the plasma pharmacokinetics of levodopa resulting from repeated, once daily, oral administration of an Opicapone (OPC)…
  • 2019 International Congress

    Exploring the experience and challenges for PD STAT clinical trial participants: a qualitative study

    T. North, J. Grose, V. Eyre, D. Webb, R. Chapman, A. Foggo, M. Webber, C. Carroll (Plymouth, United Kingdom)

    Objective: This study aims to identify the reasons why people living with Parkinson’s disease (PD) (PwP) became involved with the PD STAT randomised controlled trial…
  • 2019 International Congress

    Open-Label Study of Pimavanserin Patients With Comorbid Parkinson’s Disease and Depression

    J. Norton, D. Fredericks, G. Alva, J. Aldred, B. Coate, D. Dekarske, M. Cantillon, R. Owen (San Deigo, CA, USA)

    Objective: We are assessing use of pimavanserin (PIM) for treatment of depression in adults with PD. Background: Depression occurs in ~50% of Parkinson’s disease (PD)…
  • 2019 International Congress

    IncobotulinumtoxinA is effective, long lasting and well tolerated treatment of hemifacial spasm

    S. Ochudlo, A. Krzak-Kubica, J. Gawryluk (Katowice, Poland)

    Objective: Hemifacial spasm (HFS) is a common movement disorder characterized by involuntary contractions of the muscles innervated by facial nerve. Background: To evaluate the effect…
  • 2019 International Congress

    Opicapone improves motor and non-motor wearing off symptoms in Parkinson’s disease: an observational real-world study

    C. Oehlwein, K. Mittmann, D. Sarkisjan, J. Baron, M. Oehlwein, K. Witt (Gera, Germany)

    Objective: To assess the impact of opicapone - a third generation COMT Inhibitor - on motor and non-motor wearing off symptoms in patients suffering from…
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