Smartphone software for home monitoring of motor symptoms in Parkinson’s disease – The CloudUPDRS Smartphone Software in Parkinson’s (CUSSP) study
Objective: To determine the validity of smartphone software for objective monitoring of motor symptoms in patients with Parkinson’s disease (PD). Background: Although the MDS-Unified Parkinson’s…GLYCOPAR – A randomized, placebo-controlled, 2-arm parallel-group superiority phase II study of glycopyrrolate for moderate-to-severe sialorrhea in Parkinson’s disease
Objective: To assess the 3-month efficacy and safety of glycopyrrolate for moderate-to-severe sialorrhea in Parkinson’s disease. Background: A systematic review reported that sialorrhea affects approximately…Rivastigmine for visual hallucinations in Parkinson’s disease
Objective: The aim of the study is to investigate whether early rivastigmine treatment of visual hallucinations in patients with Parkinson's disease delays the progression of…Continuous circadian intracerebroventricular administration of anaerobic dopamine: A new therapeutic concept for Parkinson’s disease?
Objective: We aim to overcome these challenges by demonstrating that continuous i.c.v. of Anaerobic-dopamine (A-dopamine,Patent #WO2015173258 A1) close to the striatum is a feasible and…Evaluation of swallowing function by video-fluorography in patients with parkinsonism
Objective: The purpose of the present study is to investigate characteristic patterns of swallowing problems in each clinical entity of parkinsonism including Parkinson’s disease (PD)…Impact of repeated oral administration of Opicapone on the plasma pharmacokinetics of levodopa
Objective: To examine the inhibitory effect of COMT on the plasma pharmacokinetics of levodopa resulting from repeated, once daily, oral administration of an Opicapone (OPC)…Exploring the experience and challenges for PD STAT clinical trial participants: a qualitative study
Objective: This study aims to identify the reasons why people living with Parkinson’s disease (PD) (PwP) became involved with the PD STAT randomised controlled trial…Open-Label Study of Pimavanserin Patients With Comorbid Parkinson’s Disease and Depression
Objective: We are assessing use of pimavanserin (PIM) for treatment of depression in adults with PD. Background: Depression occurs in ~50% of Parkinson’s disease (PD)…IncobotulinumtoxinA is effective, long lasting and well tolerated treatment of hemifacial spasm
Objective: Hemifacial spasm (HFS) is a common movement disorder characterized by involuntary contractions of the muscles innervated by facial nerve. Background: To evaluate the effect…Opicapone improves motor and non-motor wearing off symptoms in Parkinson’s disease: an observational real-world study
Objective: To assess the impact of opicapone - a third generation COMT Inhibitor - on motor and non-motor wearing off symptoms in patients suffering from…
