Neuritic pathology in Parkinson’s Disease results from loss of anti-oxidant response activity
Objective: To determine the link between α-syn accumulation and neuritic pathology in Parkinson’s Disease (PD). Background: Neurological dysfunction in PD is highly associated with pathological…Longitudinal analysis of the modified Hoehn and Yahr disease stage in PD-1101, a Phase 1b clinical study of VY-AADC01
Objective: To describe changes over the first year in disease severity and activities of daily living using modified Hoehn and Yahr (mH&Y) stage and UPDRS…Disease-in-a-dish: drug discovery using patient-derived stem cells in Hereditary Spastic Paraplegia
Objective: Identify a drug treatment for Hereditary Spastic Paraplegia (HSP) using patient-derived stem cell models Background: HSP is a neurological disorder characterised by axonal degeneration…Texas Biorepository of Human Induced Pluripotent Stem Cells for Studying Parkinson’s Disease
Objective: To develop a biorepository of human induced pluripotent stem cells for studying Parkinson’s disease(PD). Background: Genetically engineered stem cells called “induced pluripotent stem cells”…Prevalence of Restless Leg Syndrome in the general population of Montevideo, Uruguay in 2018
Objective: A transverse study was projected in order to determine the prevalence of Restless Leg Syndrome in the general population of Montevideo, estimate the severity…Biomarkers of idiopathic REM sleep behavior disorder versus RBD within narcolepsy
Objective: We compared iRBD versus secondary RBD due to narcolepsy, searching for discriminating clinical, neurophysiological and pathological biomarkers. Background: Idiopathic REM sleep behavior disorder (iRBD)…Spinal Cord Stimulation for Severe Restless Leg Syndrome
Objective: Objectives: To report the use of spinal cord stimulation (SCS) in a patient with severe and refractory familial Restless Leg Syndrome (RLS). Background: RLS…In the shadow of Parkinson disease: what to tell patients with REM sleep behavior disorder?
Objective: To describe challenges to patient counseling in REM sleep behavior disorder (RBD). Background: RBD is a significant risk factor for development of Parkinson disease…The influence of gender, associated neurological disorder and motive for polysomnography (PSG) in the manifestations of REM sleep behaviour disorder (RBD)
Objective: To access the interrelation and relative influence of gender, associated neurological disorder and context of referral to PSG on the manifestations of (RBD). Background:…Prevalence of Rem Behavior Disorder (RBD) in different motor subtypes of Parkinson`s Disease corroborated by Polisomnography
Objective: The objective is to compare the prevalence of RBD in the different motor subtypes of Parkinson`s disease (PD), using polysomnography as the gold standard.…
