Postural instability secondary to hypoxic injury to the bilateral globus pallidi
Objective: To describe a case of post-hypoxic postural instability associated with bilateral internal globus pallidi (GP) infarcts. Background: A variety of movement disorders, including parkinsonism,…THOR 201: A Proof-of-Concept Study Assessing Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of L-dopa delivered by Impel’s Precision Olfactory Delivery (PODTM) to Parkinson’s Disease Patients in an OFF Episode (in the presence of Dopa Decarboxylase Inhibitor)
Objective: Impel NeuroPharma has developed the patient-friendly, self or caregiver actuatedPrecision Olfactory Delivery (IMPEL PODTM) device to achieve consistent upper nasal cavity drug delivery, rapid…Clinical and imaging characteristics of manifest LRRK2 and GBA carriers: The PPMI cohort
Objective: To compare baseline clinical and imaging characteristics of the GBA and LRRK2 PD manifest cohorts to PD sporadic (sPD) cohort. Background: The phenotype and…Clinical and imaging characteristics of non-manifest LRRK2 and GBA carriers: The PPMI cohort
Objective: To examine baseline clinical and dopamine transporter (DAT) imaging characteristics in a cohort of non-manifest carriers (NMC) of GBA and LRRK2 compared to healthy…Posterior cortical atrophy (PCA) attributable to corticobasal degeneration
Objective: Introduction: PCA is a clinico-radiological syndrome characterized by progressive decline in visual processing and other posterior cognitive functions, relatively intact memory and language in…Measuring perceived-health status in Parkinson’s Disease – the role of London Handicap Scale
Objective: To characterize the handicap of a broad sample of PD patients. Background: Measuring perceived-health status has an important role in Parkinson’s Disease (PD) to…Is safinamide helpful in multiple system atrophy?
Objective: To retrospectively review the clinical benefit of safinamide in patients with Multiple System Atrophy. Background: Safinamide is a new monoamine oxidase-B inhibitor, with dopaminergic…Neuromodulatory potentials of revasterol and Carpogon capitatus Roxb on the rat brain: Novel approach for Parkinson’s diseases
Objective: The aim of the current study is to explore the synergistic effects of revasterol and Carpogon capitatus extract Roxb in rotenone induced rat model…Serological analysis of circulating Alpha Synuclein protein levels by Surface Plasmon Resonance (SPR) In Parkinson’s disease
Objective: α-synuclein (α-Syn) is a presynaptic protein whose overexpression or misfolding contributes to the pathophysiology of Parkinson’s disease (PD). This study aims to estimate the…REM sleep behavior disorder and REM sleep without atonia is a progression marker in Parkinson’s disease: a report from the DeNoPa cohort
Objective: To investigate the development of REM sleep behavior disorder (RBD) and REM sleep without atonia (RWA) in Parkinson’s disease (PD) patients from the de…
