The Circulatory Levels of Serotonin, Beta endorphin and Dopamine and their relations to Pain Perception in People with Parkinson’s Disease
Objective: 1) to examine circulatory serotonin, beta-endorphin and the dopamine metabolite homovanillic acid (HVA) in people with PD, 2) to explore the relationship of the…Neural plasticity based on the change of the glutamate receptors: Repetition of electrical stimulation for the reduction of Parkinsonian symptoms
Objective: This study investigated the fundamental mechanism how the repeated electrical stimulation (ES) affects the reduction of parkinsonian symptoms. Background: The reduced parkinsonian symptoms by…Skin could be the new peripheral tissue of interest in Parkinson’s disease transcriptomics
Objective: Profiling gene expression changes in peripheral tissues in PD. Background: Obtaining tissue for gene expression analysis in PD from CNS is done post mortem.…Synchronization Study of Regional Local Field Potential in Rat with Dopamine Receptor Stimulation
Objective: The aim of this study attempts to explore the non-linear interaction with cross-frequency coupling in rats during the stimulation of dopamine receptors. Background: Investigating…Dopamine substitution increases connectivity between premotor and motor areas in Parkinson’s disease – a DCM-Study
Objective: To assess the influence of dopaminergic depletion in Parkinson’s disease (PD) on connectivity parameters within the cortical motor network. Background: Integration of neuronal information…The interaction between iron metabolism and inflammation in Parkinson´s disease: an in vivo and post mortem study
Objective: To assess the relationship iron and inflammatory markers in an in vivo and post mortem study of Parkinson´s disease subjects. Background: Although neuroinflammation and…Pathological role of GBA2 in GBA1-related disorder
Objective: This study was performed to determine the pathological role of the non-lysosomal β-Glucosidase (GBA2) in the CNS in Gaucher’s disease (GD) and GBA1-related Parkinson's…Translation of a subject-specific stereotaxic platform to a large animal deep brain stimulation research models
Objective: To evaluate the feasibility and accuracy of applying the commercially-available, FHC STarFix platform system for direct targeting of deep brain stimulation electrodes in a…Mitigation Effects of a Novel Herbal Medicine Hepad, on neurophysiology.
Objective: Therefore, further studies are needed to identify compounds that can modulate the disease process and prevent the progression of symptoms in affected patients. Our…Blood Metagenomics Analyses of Brazilian Parkinson’s Disease Patients: A Clinical Substype Study
Objective: The goal of this study is to analyze the dormant microbiome present in blood of Parkinson’s disease (PD) patient and healthy controls samples by…
