Preserved white matter microstructure in Parkinson’s disease patients with levodopa-induced dyskinesia: Evaluation by neurite orientation dispersion and density imaging (NODDI)
Objective: Brain microstructure alteration using MRI in Parkinson's disease (PD) have not been well studied. We analysis the white matter alterations in Parkinson’s disease with…Neuroradiological differences between patients with akinesia-dominant and tremor-dominant Parkinson’s disease
Objective: To compare the metabolism of the putamen and the cerebral cortex between the akinesia-dominant group and the tremor-dominant group of Parkinson's disease (PD) patients.…Probing Error Signals of Postural Control in Fragile X Premutation carriers
Objective: This study aimed to characterize cortical theta activity in Fragile X Premutation carriers during continuous balance. Background: Fragile X Associated Tremor/Ataxia Syndrome (FXTAS) is…Structural connectivity changes in G2019S-LRRK2 gene mutation carriers without manifest Parkinson’s disease
Objective: We hypothesised that abnormal sprouting of serotonergic terminals in the hypothalamus may lead to abnormal structural connectivity, which can be measured with diffusion tensor…Mitochondrial Complex 1, Sigma 1 Receptor and Synaptic Vesicle protein 2A density in early de novo patients with Parkinson’s Disease: pilot PET data
Objective: In this study, we evaluated the density of Mitochondrial complex 1 (MC1), sigma 1 receptor (s1R) and Synaptic Vesicle protein 2A (SV2A) in early…Comparison of PDE10A and DAT expression as markers of disease burden in early Parkinson’s disease
Objective: We aimed to compare loss of PDE10A and DAT expression in patients with Parkinson’s disease. Background: Recent work has shown loss of PDE10A expression…Age-related failure in compensatory mechanisms and its relation to the Parkinson phenotype: evidence from a SPECT study in early and late-onset PD
Objective: To investigate if a less prominent dopaminergic dysfunction on 123I-ioflupane SPECT imaging (DaTSCAN) despite a more severe motor phenotype in Late Onset Parkinson’s Disease…Structural imaging changes in hepatic and neurological Wilson disease
Objective: To quantitatively assess cerebral structural changes in Wilson disease (WD) subjects with hepatic and neurological phenotypes. Background: WD is a rare autosomal recessive disorder…Extrastriatal dopaminergic and serotonergic pathways in Parkinson’s disease and in dementia with Lewy bodies: a 123I-FP-CIT study
Objective: To evaluate the common and divergent dopaminergic and serotonergic impairment in Parkinson's disease and dementia with Lewy bodies using 123I-FP-CIT imaging. Background: Striatal dopaminergic…Different patterns of brain activity during lower limb movements in Parkinson’s disease patients with and without freezing of gait
Objective: To assess brain functional MRI (fMRI) activity during a feet movement task in Parkinson’s disease patients with (PD-FoG) and without freezing of gait (PD-noFoG)…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.