MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2019 International Congress

    Potential involvement of the caudate nucleus in GBA-associated Parkinson’s disease

    MC. Ruppert, A. Greuel, M. Tahmasian, F. Maier, T. van Eimeren, K. Lohmann, L. Timmermann, M. Tittgemeyer, A. Drzezga, C. Eggers (Marburg, Germany)

    Objective: Multimodal functional assessment of striatocortical loop integrity in Parkinson’s Disease (PD) patients with and without GBA variants Background: Biallelic GBA mutations provoke the lysosomal…
  • 2019 International Congress

    Micro structural Changes in Substantia Nigra are associated with Severity of Parkinson’s Disease.

    A. Safai, S. Rane, S. Prasad, J. Saini, P. Pal, M. Ingalhalikar (Pune, India)

    Objective: The aim of this study was to apply diffusion tensor imaging (DTI) to evaluate atrophy of the Substantia Nigra pars compacta (SNc), the pathological…
  • 2019 International Congress

    Dual-task in Parkinson’s disease: a gait analysis and functional MRI study

    E. Sarasso, A. Gardoni, S. Galantucci, A. Tettamanti, MA. Volontè, M. Filippi, F. Agosta (Milan, Italy)

    Objective: To study gait parameters and functional MRI (fMRI) patterns performing dual-task in Parkinson’s disease patients with postural instability and gait disorders phenotype (PD-PIGD) and…
  • 2019 International Congress

    Genotype influences circuit compensation in Parkinson’s disease

    K. Schindlbeck, A. Vo, N. Nguyen, C. Tang, M. Niethammer, V. Dhawan, V. Brandt, R. Saunders-Pullman, S. Bressman, D. Eidelberg (Manhasset, NY, USA)

    Objective: This study investigates differences in brain network organization in patients with Parkinson’s disease (PD) with genetic risk factors relative to sporadic PD patients and…
  • 2019 International Congress

    Sleep Disturbances in Essential Tremor: A pilot investigation of the related brain microstructural changes using diffusion tensor imaging

    YIL. Sengul, HAF. Otcu, ISM. Ustun, HAK. Sengul, ALP. Alkan (Istanbul, Turkey)

    Objective: In this pilot exploratory study, we aimed to search possible related brain microstructural changes of sleep disturbances (SD) in essential tremor  (ET) patients. Background:…
  • 2019 International Congress

    Functional connectivity within the cerebellum and brainstem in essential tremor patients– a tailored resting state fMRI approach

    S. Sharifi, ES. Scheijbeler, WVP. Potters, AFR. Rootselaar (Amsterdam, Netherlands)

    Objective: To better understand the pathophysiology of essential tremor (ET) by analysing brainstem and cerebellar neuronal circuitry activity with tailored fMRI resting state methods. Background:…
  • 2019 International Congress

    Ponto-cortical aberrations:Neural correlations for Hypomimia in PD

    P. Singru, V. Vadiyala, E. Ganesh, V. Vinodhanand (Georgetown, Guyana)

    Objective: We team neuron, focused on analyzing progressive degeneration of neural structural connectivity of the tract from Brodmann area 4, part precentral gyrus to facial motor…
  • 2019 International Congress

    Cortical cholinergic dysfunction correlates with microglial activation in the Substantia Innominata in patients with REM sleep behavior disorder

    K. Stær, A. Iranzo, M. Stokholm, K. østergaard, M. Eroles, M. Otto, K. Svendsen, A. Pla, D. Vilas, J. Santamaria, A. Møller, C. Gaig, P. Borghammer, D. Brooks, E. Tolosa, N. Pavese (Aarhus N, Denmark)

    Objective: To explore possible correlations between levels of microglial activation (neuroinflammation) in the Substantia Innominata (SI), the major source of cholinergic input to the cortex,…
  • 2019 International Congress

    Amyloid load and cognitive decline in Parkinson’s disease: preliminary longitudinal findings

    M. Stark, T. Melzer, D. Myall, R. Keenan, T. Pitcher, KL. Horne, L. Livingston, M. Macaskill, J. Dalrymple-Alford, T. Anderson (Christchurch, New Zealand)

    Objective: To test for any association between amyloid deposition and future cognition in Parkinson’s disease, in a sample enriched for mild cognitive impairment. Background: Progressive…
  • 2019 International Congress

    Hemispheric Differences in Motor Circuitry of Parkinson’s disease: Metabolism and Micro-Structure

    DAN. Stein, N. Goldberg, L. Domachevsky, H. Bernstine, M. Nidam, D. Groshar, M. Lorberboym, S. Israeli-Korn, M. Gomori, Y. Assaf, S. Hassin-Baer (Tel-Aviv, Israel)

    Objective: The purpose of this study was to quantitatively characterize simultaneous PET/MR brain changes focusing on the hemispheric asymmetry to trace differences between the more…
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