MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2018 International Congress

    Effects of droxidopa when measuring gait speed, kyphosis, and functional reach in Parkinson’s disease

    C. Kutz, L. Adams, E. Moncheski (Colorado Springs, CO, USA)

    Objective: To determine if droxidopa improves gait speed, kyphosis, and functional reach in Parkinson’s disease when added to routine care treatment. Background: Fall risk factors…
  • 2018 International Congress

    Bipolar directional DBS in VIM-stimulated patients

    J. Steffen, P. Reker, F. Mennicken, T. Dembek, H. Dafsari, G. Fink, V. Visser-Vandewalle, M. Barbe (Cologne, Germany)

    Objective: To compare circular, directional and bipolar stimulation in VIM-implanted PD- and ET-patients regarding effect and side-effect thresholds in a cross-sectional design. Background: So far,…
  • 2018 International Congress

    Improvements of tremor control and life quality of refractory essential tremor patients after MR-guided focused ultrasound thalamotomy – A Taiwan experience

    H.C. Lai, K. Tsai, W.C. Chang, T. Taira, C.Y. Wei (Changhua County, Taiwan)

    Objective: To quantify the tremor control and life quality changes of refractory essential tremor (ET) patients after the MR-guided focused ultrasound (MRgFUS) thalamotomy in Taiwan.…
  • 2018 International Congress

    INTREPID: A Prospective, Double Blinded, Multicenter Randomized Controlled Trial Evaluating Deep Brain Stimulation with a New Multiple Source, Constant Current Rechargeable System in Parkinson’s disease

    J. Vitek, R. Jain, L. Chen, I. Study Group, P. Starr (Minneapolis, MN, USA)

    Objective: INTREPID is designed to assess the improvement in motor function and quality of life in patients with Parkinson’s disease (PD) following Deep Brain Stimulation…
  • 2018 International Congress

    Specific active immunotherapy (SAIT) against alpha-synuclein with AFFITOPE® PD01A and PD03A: Results from the AFF009 phase I trial

    W. Meissner, A. Pavy-Le Traon, A. Foubert-Samier, M. Galitzky, B. Laurens, U. Sabatini, S. Schmidhuber, D. Winter, G. Galabova, G. Staffler, A. Schneeberger, A. Kutzelnigg, O. Rascol (Bordeaux Cedex, France)

    Objective: Phase I study with AFFITOPE® PD01A and PD03A to assess safety and tolerability as well as immunogenicity of this approach in MSA patients. Background:…
  • 2018 International Congress

    PASSPORT, An Ongoing Phase 2 Study in Patients with PSP– Baseline Characteristics

    T. Dam, A. Boxer, L. Golbe, G. Höglinger, H. Morris, I. Litvan, J.C. Corvol, A. Lang, C. Bechtold, I. Qureshi, M. Grundman, B. Han, J. O'Gorman, T. Olsson, S. Budd Haeberlein (Cambridge, MA, USA)

    Objective: To describe baseline characteristics of the participants with progressive supranuclear palsy (PSP) enrolled in the ongoing PASSPORT (NCT03068468) phase 2 study. Background: PSP is…
  • 2018 International Congress

    A German-Austrian multicenter, non-interventional, prospective study for the treatment with abobotulinumtoxinA injections in naïve and previously treated patients suffering from cervical dystonia

    W. Jost, A. Schramm, M. Müngersdorf, A. Stenner, P. Schwingenschuh, P. Maisonobe, M. Koch, B. Haslinger (Wolfach, Germany)

    Objective: In this prospective, multicenter, non-interventional study (NCT01840462) the primary objective was effectiveness of abobotulinumtoxinA in BoNT treatment-naïve and previously treated subjects after two injection…
  • 2018 International Congress

    Background: Transcranial magnetic stimulation (rTMS) may influence the progression of PD

    J. Málly (Sopron, Hungary)

    Objective: We hypothesized that the regularly repeated rTMS would decrease the development of PD and that there might be a synergistic effect with transcranial direct…
  • 2018 International Congress

    Effect of PD medication on disease progression as measured by rate of change in MDS_UPDRS and DaT SBR in PPMI study

    J. Cedarbaum, K. Evans, M. Yang, J. Xiao (Cambridge, MA, USA)

    Objective: In clinical trials for new PD therapies, it is common for patients to start to take approved symptomatic PD medications during the study. The…
  • 2018 International Congress

    Low-Fat Versus Ketogenic Diet In Parkinson’s Disease: A Pilot Randomized Controlled Trial

    M. Phillips, D. Murtagh, L. Gilbertson, F. Asztely, C. Lynch (Hamilton, New Zealand)

    Objective: To compare the plausibility, safety, and efficacy of a low-fat, high-carbohydrate diet versus a ketogenic diet in a hospital clinic of PD patients. Background:…
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