MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2019 International Congress

    The Dutch Parkinson and Cognition study (DUPARC): Cognitive impairment and cholinergic innervation in de novo Parkinson’s Disease patients

    S. Vander Zee, JM. Boertien, MJJ. Gerritsen, JM. Spikman, T. van Laar (Groningen, Netherlands)

    Objective: To explore the incidence and characteristics of early cognitive impairment in Parkinson’s disease (PD) patients and the relationship with regional cholinergic innervation. Background: Cognitive…
  • 2019 International Congress

    Neuroimaging in Parkinson’s disease dementia: Connecting the dots

    R. Weil, J. Hsu, R. Darby, L. Soussand, M. Fox (Nashville, TN, USA)

    Objective: To identify the neural substrates of Parkinson’s disease dementia (PDD) and Parkinson’s disease with Mild Cognitive Impairment (PD-MCI) using a network mapping approach. Background:…
  • 2019 International Congress

    Evaluation of Imidazoline 2 binding sites reflecting astroglia pathology in Parkinson’s Disease: An in vivo [11C]BU99008 PET study

    H. Wilson, G. Dervenoulas, G. Pagano, R. Tyacke, J. Myers, R. Gunn, E. Rabiner, D. Nutt, M. Politis (London, United Kingdom)

    Objective: We aimed to evaluate the role of astroglia activation in Parkinson's disease (PD) using [11C]BU99008 PET, a novel radioligand with high specificity and selectivity…
  • 2019 International Congress

    Evaluation of Imidazoline 2 binding sites reflecting astroglia pathology in Huntington’s Disease: An in vivo [11C]BU99008 PET study

    H. Wilson, F. Niccolini, G. Dervenoulas, R. Tyacke, J. Myers, R. Gunn, D. Nutt, E. Rabiner, S. Tabrizi, M. Politis (London, United Kingdom)

    Objective: We aimed to evaluate the role of astroglia activation in Huntington’s disease gene expansion carriers (HDGECs) using [11C]BU99008 PET, a novel radioligand with high specificity and…
  • 2019 International Congress

    The role of Synaptic vesicle protein 2A (SV2A) in patients with Parkinson’s disease dementia and Dementia with Lewy bodies: An in vivo [11C]UCB-J PET study

    H. Wilson, G. Dervenoulas, G. Pagano, A. Chandra, F. Niccolini, M. Esposito, R. Gunn, L. Ricciardi, E. Rabiner, D. Aarsland, M. Politis (London, United Kingdom)

    Objective: We aimed to investigate the role of synaptic vesicle glycoprotein 2A (SV2A) in Parkinson’s disease dementia (PDD) and Dementia with Lewy bodies (DLB) using…
  • 2019 International Congress

    Regional subcortical volumes predict gait decline in early Parkinson’s disease

    J. Wilson, R. Lawson, B. Galna, A. Yarnall, S. Lord, R. Morris, L. Alcock, G. Duncan, T. Khoo, D. Burn, L. Rochester, J-P. Taylor (Newcastle Upon Tyne, United Kingdom)

    Objective: To predict changes in discrete gait characteristics in early Parkinson’s disease (PD) compared to healthy ageing, using subcortical brain volumes quantified in early disease.…
  • 2019 International Congress

    Distributed Global Functional Connectivity Networks Predict Responsiveness to L-DOPA and Subthalamic Deep Brain Stimulation

    C. Wu, T. Foltynie, P. Limousin, L. Zrinzo, H. Akram (Philadelphia, PA, USA)

    Objective: To investigate global resting-state functional connectivity (rsFC) patterns associated with response to L-DOPA and to subthalamic nucleus (STN) deep brain stimulation (DBS) in patients…
  • 2019 International Congress

    The neural representations of the voice tremor spectrum

    L. Xavier, K. Simonyan (Boston, MA, USA)

    Objective: Investigate shared and disorder-specific brain abnormalities in essential and dystonic tremor of voice using functional and structural brain imaging. Background: Essential tremor of voice…
  • 2019 International Congress

    Multi-modal MRI in patients with genetically confirmed familial cortical myoclonic tremor with epilepsy type 1

    F. Xie, B. Wang, J. Wang, Z. Cen, W. Wei, Y. Chen, H. Sun, D. Yang, Y. Lou, X. Chen, S. Chen, H. Wang, L. Wang, S. Wang, X. Qiu, Y. Ding, H. Yin, S. Wu, B. Zhang, Y. Zang, W. Luo (Hangzhou, China)

    Objective: The present study utilized multi-modal MRI study to investigate the structural and functional alterations in genetically confirmed familial cortical myoclonic tremor with epilepsy type…
  • 2018 International Congress

    Ankle proprioception and postural instability in Parkinson’s disease

    H. Teasdale, E. Preston, W. Spratford, G. Waddington (Bruce, Australia)

    Objective: To determine: 1. Is there a correlation between central and peripheral proprioception in Parkinson’s disease? 2. Does postural instability increase with lack of vision…
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