Switching from double-blind entacapone or placebo to open-label opicapone: UPDRS-II and III results of the 1-year extension BIPARK-I study
Objective: To evaluate the impact on UPDRS-II and III in levodopa-treated Parkinson’s Disease (PD) patients who switched from placebo (PLC) or entacapone (ENT) to opicapone…Gait speed after applying anodal-transcranial Direct Current Stimulation in people with Parkinson’s disease? Preliminary results
Objective: The objective of this study was to explore the effects of anodal-tDCS with two different montages on gait speed in people with PD. Background:…Effects of the Lee Silverman Voice Treatment (LSVT LOUD ®) on Facial Expressivity in Individuals with Parkinson’s Disease (PD) as a function of Emotional Valence
Objective: To examine the effect of LSVT LOUD (Ramig et al., 2011) on facial expressivity in PD as a function of emotional valence. Background: Research…Dyskinesia management in COMT-naïve patients starting adjunctive therapy with opicapone: The BIPARK-I double-blind experience
Objective: To elucidate which levodopa-treated COMT-naïve Parkinson’s Disease (PD) patients were at higher risk for developing dyskinesia when starting opicapone (OPC) 50mg or entacapone (ENT).…Efficacy of opicapone in Parkinson’s disease patients with ‘early’ motor fluctuations: Responder analyses from the BIPARK-I double-blind experience
Objective: To evaluate, in levodopa-treated Parkinson’s Disease (PD) patients with ‘early’ motor fluctuations, the proportion of patients (ie, responders) achieving at least a 1-h reduction…A Phase 2A Study of Nilotinib in Patients with Advanced and Early Parkinson’s disease: Study Design
Objective: To assess the safety and tolerability of nilotinib (150-300 mg QD) in moderate/advanced and early/de novo Parkinson disease (PD) participants. Background: Studies in cell…Delayed-onset Edema Surrounding Deep Brain Stimulation Leads: Insights From A Case Series and Literature Review
Objective: We report a case that showed Postoperative cerebral edema around a deep brain stimulation (DBS) electrode and review the literature to explore its possible causes. Background: Deep brain…Variation in the L-dopa motor response in pathologically confirmed Parkinson’s disease
Objective: To examine the L-dopa-response (improvement in motor symptoms) in published cases of pathologically confirmed Parkinson’s disease (PD). Background: L-dopa responsiveness supports the diagnosis of…Effectiveness and safety of acupuncture in the treatment of Parkinson’s disease: A systematic review and meta-analysis of randomized controlled trials
Objective: This study aimed to examine the effectiveness and safety of acupuncture in the treatment of Parkinson’s disease (PD). Background: Background: Several previous studies have…Impact of SYN120 (a Dual 5-HT6/5-HT2A antagonist) on psychiatric symptoms in patients with Parkinson’s disease dementia: Results from a Phase 2a Study
Objective: To assess the psychiatric effects of SYN120 in patients with Parkinson's disease dementia (PDD). Background: SYN120 is a dual antagonist of serotonin (5-HT6 and…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.