Microglial activation, white matter and hippocampal damage correlate with cognitive impairment in chronic cerebral hypoperfused and MPTP-lesioned mice
Objective: We hypothesize that cerebral hypoperfusion may influence the cognitive function of PD animal models. To investigate the effects of cerebral hypoperfusion and microangiopathy on…Investigating the role of microRNA biogenesis pathway in neuroprotection in primary neuronal culture model of Parkinson’s disease
Objective: Here we study the effect of microRNAs (miRs) biogenesis on the dopamine (DA) neuronal maintenance and protection from different stressor-induced insults. Background: Despite many…Classification of Dopaminergic-State and Motor Activity by Theta, Beta and Gamma Activity in Parkinson’s Disease
Objective: To test whether machine learning algorithms are suitable to classify dopamine and behavioral states in Parkinson’s patients (PD). Background: While motor symptoms of PD…The Prevalence of Tandem Gait Abnormality in Parkinson’s Disease
Objective: To assess the prevalence of tandem gait abnormality in patients with Parkinson’s disease (PD), comparing Hoehn and Yahr (HY) stages 2 and 3. Background:…Prevalence and risk factor of peak-dose dyskinesia in Thai patients with Parkinson’s disease
Objective: To determine the prevalence and risk factors associated with peak-dose dyskinesia in Thai patients with Parkinson’s disease. Background: Dyskinesias are involuntary movement that interfere…Cortical correlates of dual-task turning with and without freezing of gait
Objective: This study investigated the relationship between prefrontal cortex (PFC) activity and turning characteristics with and without a dual-task in in people with Parkinson’s disease…Automated immunohistochemical detection of pathological alpha-synuclein in human tissue biopsy
Objective: The goals of this study were to create a highly sensitive brightfield immunohistochemical (IHC) assay for pathological alpha-synuclein (aSyn) in formalin-fixed, paraffin embedded (FFPE)…Natural occurring antibodies reduce aggregation of α-synuclein
Objective: We tested naturally occurring antibodies (nAbs) against α-synuclein both in vitro as well as in HEK293T cells to determine binding, cell viability and capacity…Peripheral Inflammatory Mediators in Parkinson’s Disease – A Potential Biomarker
Objective: i.To determine if post-translationally modified phosphorylated α-synuclein levels are altered in the peripheral blood of Parkinson’s disease (PD) patients compared to control subjects. ii.To…A metabolomic signature of treated and drug-naïve patients with Parkinson disease: A pilot study
Objective: The aim of our case–control study is to compare entire blood metabolomic profiles obtained from treated PD patients, de novo PD patients and controls,…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.