MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2018 International Congress

    α-synuclein antibody 5G4 identifies manifest and prodromal Parkinson’s disease in colonic mucosa

    M. Skorvanek, E. Gelpi, E. Mechirova, Z. Ladomirjakova, V. Han, N. Lesko, E. Feketeova, J. Ribeiro Ventosa, F. Kudela, K. Kulcsarova, S. Babinska, S. Toth, L. Gombosova, F. Trebuna, M. Lutz, Z. Gdovinova, G. Kovacs (Kosice, Slovakia)

    Objective: The aim of this study was to evaluate colonic mucosa staining using the 5G4 antibody, specific only for the disease-associated form of α-synuclein, in…
  • 2018 International Congress

    Dietary habits, motor and cognitive impairment in Parkinson’s Disease

    A. Pilotto, MC. Rizzetti, m. Oppini, C. passeri, A. Alberici, R. Turrone, M. Cosseddu, D. Placidi, M. Turla, b. Borroni, R. Lucchini, A. Padovani (Brescia, Italy)

    Objective: To evaluate the relationship between dietary habits, motor and cognitive impairment in Parkinson's disease patients with both cross-sectional and longitudinal design Background: Diet and…
  • 2018 International Congress

    Saccades in Parkinson’s disease: Hypometric, slow, or maladaptive?

    L. Neilson, F. Ghasia, A. Shaikh (Cleveland, OH, USA)

    Objective: Quantitatively study visually-guided saccades (VGS) in Parkinson’s disease (PD). Background: Visuomotor deficits such as hypometric VGS are present in PD despite the retained ability…
  • 2018 International Congress

    Modulation of CaMKIIa-NR2B interaction in levodopa-induced dyskinesia in 6-OHDA- lesioned Parkinson’s rats

    XS. Wang, WW. Wang, CL. Xie (Wenzhou, China)

    Objective: In the present study, therefore, we examined the relationship between CaMKII and NR2B in levodopa-induced dyskinesia rats. Background: Long-term treatment with L-dopa leads to…
  • 2018 International Congress

    Alpha-synuclein oligomer and rotenone treatments injury the dopaminergic neuron via inhibiting the expression of gene SEMA6D

    X. Yingyu (Guangzhou, China)

    Objective: To investigate the expression of Semaphorin6D (SEMA6D) and its interaction with Plexin-A1 in cellular Parkinson's disease(PD) models induced by α-synuclein and rotenone. Background: In…
  • 2018 International Congress

    Neuropathological correlates of psychiatric disorders in PD

    J. Hinkle, N. Fischer, K. Perepezko, C. Bakker, M. Broen, A. Butala, T. Dawson, A. Leentjens, Z. Mari, C. Marvel, K. Mills, E. Moukheiber, A. Pantelyat, O. Pletniková, L. Rosenthal, M. Shepard, J. Troncoso, J. Wang, G. Pontone (Baltimore, MD, USA)

    Objective: To test the hypothesis that neuropsychiatric symptoms (NPS) in PD are associated with histopathologically confirmed neuronal loss and gliosis (NLG) in the locus coeruleus…
  • 2018 International Congress

    Correlation between mood and behavioral disorders and quality of life in patients with Parkinson’s disease

    O. Galceava, A. Mita, L. Giurgiulescu, R. Latea, V. Tudorica, D. Gheonea, D. Stanca (Craiova, Romania)

    Objective: The aim of this study was to investigate if the mood and behavioral disorders could be correlate with quality of life in patients with…
  • 2018 International Congress

    Depression (BDI-II) in Parkinson’s disease: Prevalence, types, and variables associated to major, minor and subclinical depression in COPPADIS cohort

    M. Aguilar, P. Pastor, M. Almeria, I. Alvarez, S. Arribas, I. Gonzalez, M. Sierra, J. Infante, A. Avila, M. Catalan, F. Alonso, C. Villanueva, L. Lopez, V. Nogueira, V. Puente, A. Crespo, J. Garcia, F. Damas, E. Pacheco, P. Martínez-Martin, D. Santos, G. Coppadis (Terrassa, Spain)

    Objective: To know the prevalence and characteristics of depression in PD patients of the COPPADIS-2015 cohort and its relationship with the other clinical aspects of…
  • 2018 International Congress

    Evaluation of affective temperament and bipolarity among patients with Parkinson’ s disease

    Y. Degirmenci, K. Altinbas, H. Kececi (Duzce, Turkey)

    Objective: To compare the bipolarity and affective temperament scores between patients with Parkinson’s Disease (PD) and healthy controls. Background: Mood disorders are the most common…
  • 2018 International Congress

    Pimavanserin Combined With Anti-Dementia Medications for Parkinson Disease Psychosis

    A. Espay, M. Guskey, N. Larsen, B. Coate, J. Vizcarra, S. Factor, J. Friedman, D. Weintraub, A. Lang (Cincinnati, OH, USA)

    Objective: To evaluate the differential antipsychotic effect of pimavanserin, a selective serotonin (5-HT2A) receptor inverse agonist, for Parkinson’s disease psychosis with and without concomitant anti-dementia…
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