Joint pain as premonitory urge in patient with Ehlers Danlos Syndrome and Tourette’s Syndrome
Objective: We report the case of a 21 year old male with Ehlers-Danlos syndrome (EDS) and Attention Deficit Hyperactivity Disorder (ADHD) who presented with joint…Tourettism associated with the Xq25 Microduplication Syndrome
Objective: To present a novel case of Tourettism emerging within the Xq25 microduplication syndrome. Background: Tourette syndrome (TS) is a childhood-onset neurobehavioral disorder hallmarked by…Long-term effect of botulinum toxin injection in the external oblique muscle to treat camptocormia in three patients with Parkinson’s disease.
Objective: To examine long-term effect of botulinum toxin injection (BTX) in the external oblique muscle (EO) for camptocormia associated with Parkinson’s disease (PD). Background: Camptocormia…Basal Ganglia Circuits for Motor and Behavioral, Emotional Performances
Objective: The present study aimed to identify which neurons in the basal ganglia (BG) target dopaminergic or GABAergic neurons in SN pars compacta (SNc) or…Aquatic Dual Task Exercise: Effects on Body Balance of Individuals with Parkinson’s Disease
Objective: To verify the effect of a dual task (DT) aquatic exercise program on the balance (static and dynamic) of individuals with Parkinson's disease (PD)…MitoQ and Reduced Glutathione Protects Against Dopamine Induced Brain Mitochondrial Electron Transport Chain Inhibition During Extended In Vitro Incubation: Involvement of Free Radicals and Quinone Products
Objective: To study the impact of MitoQ and GSH against DA induced rat brain mitochondrial electron transport chain inhibition during extended in vitro incubation. Background:…Levodopa responsiveness in Parkinson’s disease is significantly impaired in those with diabetes and increased vascular risk.
Objective: To define variation in L-dopa response in recent onset PD. Background: L-Dopa responsiveness is a defining feature of Parkinson’s disease (PD), but the degree…Efficacy and safety of incobotulinumtoxinA (inco/A) for essential tremor using kinematics-guided clinical decision support: A randomized, double-blind, placebo-controlled trial
Objective: To demonstrate improvement of arm tremor severity and hand function with kinematics-guided inco/A therapy Background: Botulinum neurotoxin A (BoNT-A) therapy of debilitating tremor symptoms…Rationale and Design of a Phase 2 Study to Evaluate the Efficacy of Intepirdine (RVT-101) in Improving Gait and Balance in Patients with Dementia
Objective: To describe the rationale and design of a Phase 2 study that evaluates the effect of intepirdine (RVT-101) on gait and balance in patients…A Phase 2 Study of Nelotanserin, a Novel 5HT2A Receptor Inverse Agonist, in Dementia with Lewy Bodies and Parkinson’s Disease Dementia Subjects Experiencing Visual Hallucinations
Objective: To evaluate the safety and efficacy of nelotanserin in Lewy body dementia subjects experiencing visual hallucinations. Background: Nelotanserin is a selective 5HT2A receptor inverse…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.