Brain structural and functional changes associated with frequent falls in Parkinson’s disease
Objective: We investigated brain structural and functional changes associated with falls. Background: Gait and balance disorders are one of the common clinical features of Parkinson’s…Clinical and Imaging and phenoconversion in the PARS prodromal cohort
Objective: We report clinical and imaging phenoconversion data at 6 years follow-up for the PARS cohort. Background: The PARS cohort consists of 203 hyposmic and…The effect of expectation on Parkinson’s Disease: an EEG study
Objective: The aim of the present study is to determine how the expectation of receiving a therapeutic treatment influences Parkinson’s disease (PD) symptoms. Background: The…Decreased Fronto-Parietal connection is associated with face pareidolia in Parkinson’s disease.
Objective: To investigate the neural mechanism of face pareidolia in Parkinson’s disease (PD) patients using resting state functional magnetic resonance imaging (rs-fMRI). Background: Face pareidolia…Early caudate involvement in Parkinson’s disease may predict future cognitive decline
Objective: 1. To investigate prevalence of caudate dopaminergic dysfunction as measured by 123I-FP-CIT in a large cohort of early stage (< 2 years disease duration)…Neural correlates of minor hallucinations in Parkinson’s disease: A multimodal imaging study
Objective: To explore the neural correlates sub-serving isolated minor hallucinations in Parkinson's disease (PD) through a multimodal structural and functional neuroimaging approach based on grey matter…Striato-cortical connections in Parkinson’s and Alzheimer’s diseases: relation to cognition
Objective: To evaluate resting-state striato-cortical connectivity in PD and mild cognitive impairment due to Alzheimer's disease (AD-MCI) and assess their relation to cognitive outcomes. We…Marked occipital hypometabolism on FDG-PET in patients with idiopathic RBD may predict Parkinson’s disease
Objective: In the present study, we tried to elucidate if the occipital hypometabolism detected by [(18) F]-fluoro-d-glucose (FDG) positron emission tomography (PET) scan in patients with idiopathic…Utility of DaTscan Imaging in Differentiating Drug Induced Parkinsonism from IPD and Other Forms of Parkinsonism
Objective: To determine clinical correlates which differentiate drug induced Parkinsonism (DIP) from IPD and other forms of Parkinsonism using DaT-SPECT imaging. Background: DaT-SPECT imaging is…Global Regulatory Agencies Support the Use of Dopamine Transporter Neuroimaging for Subject Selection in Clinical Trials Targeting Early Stage Parkinson’s Disease – on behalf of Critical Path for Parkinson’s (CPP) Consortium
Objective: A key goal of the Critical Path for Parkinson’s Consortium (CPP) is to qualify, with regulatory agencies, drug development tools for use in PD…
